{"id":"W2529960926","doi":"10.1038/srep34939","title":"mTOR is critical for intestinal T-cell homeostasis and resistance to Citrobacter rodentium","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; U.S. Department of Veterans Affairs","keywords":"Citrobacter rodentium; mTORC1; Biology; mTORC2; Homing (biology); PI3K/AKT/mTOR pathway; Mesenteric lymph nodes; Intraepithelial lymphocyte; T cell; Lamina propria; Cell biology; CD8; Immunity; Effector; Intestinal mucosa; Immunology; Cancer research; Immune system; Signal transduction; Medicine; Epithelium; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001618148,0.0004459551,0.00027035,0.0003540402,0.0002421673,0.0005266969,0.0002244791,0.0003786325,0.0008054913],"category_scores_gemma":[0.0001706979,0.000184851,0.0001643098,0.0001389082,0.0003312088,0.0002355485,0.0002900662,0.0003835595,0.0004314199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002608481,"about_ca_system_score_gemma":0.0002637722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003836842,"about_ca_topic_score_gemma":0.0004404249,"domain_scores_codex":[0.9998232,0.00002752465,0.00002241794,0.00004494674,0.00004184003,0.00004011154],"domain_scores_gemma":[0.9998518,0.00001134472,0.00006392426,0.00000923828,0.00002013024,0.00004353547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003489409,0.00002322668,0.0006757611,0.0001396429,0.000009925134,0.0001413293,0.00001648692,0.0001555512,0.9933427,0.0002528119,0.0002003609,0.004693267],"study_design_scores_gemma":[0.00005782959,0.0005192868,0.04077924,0.00004935674,0.00008025139,0.001701579,0.0001082805,0.002370775,0.9383467,0.0005071889,0.01545742,0.00002218598],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9746404,0.01603942,0.003043895,0.0004870446,0.00008169957,0.00003608931,0.0006566335,0.0003709861,0.004643795],"genre_scores_gemma":[0.992376,0.00319608,0.002235785,0.00006870474,0.00003275718,0.00002525706,0.0004633938,0.00003653787,0.001565511],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008054913,"threshold_uncertainty_score":0.002694666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01411484511205318,"score_gpt":0.2470294764398763,"score_spread":0.2329146313278231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}