{"id":"W2529979203","doi":"10.1182/blood.v122.21.2445.2445","title":"The Splicing Factor Heterogeneous Nuclear Ribonucleoprotein L (hnRNPL) Restricts p53 Dependent and p53 Independent Cell Death Pathways In Hematopoietic Stem Cells","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"Biology; RNA splicing; Haematopoiesis; Stem cell; Alternative splicing; Embryonic stem cell; Exon; Cell biology; Progenitor cell; RNA-binding protein; Ribonucleoprotein; Hematopoietic stem cell; Splicing factor; Transgene; Molecular biology; Genetics; Gene; Messenger RNA; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009762729,0.000192189,0.0001473746,0.000191884,0.00009668048,0.000205496,0.0001658521,0.0001740468,0.0009105678],"category_scores_gemma":[0.0000684213,0.0001009685,0.0001640487,0.00007126274,0.0001980293,0.0001084985,0.0002207728,0.000238102,0.0004211269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001743678,"about_ca_system_score_gemma":0.0001093519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000313982,"about_ca_topic_score_gemma":0.0006126267,"domain_scores_codex":[0.9998921,0.00001700707,0.000008928869,0.00002628962,0.00003316189,0.00002246557],"domain_scores_gemma":[0.9999149,0.00001719507,0.00002755112,0.00001192722,0.000008273619,0.00002024383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002575481,0.000005854588,0.0001789408,0.00001260922,0.00000157848,0.00003292457,0.000004573668,0.00002994573,0.9989359,0.00005961181,0.00002610799,0.0006863493],"study_design_scores_gemma":[0.00001146295,0.0001677544,0.004346552,0.000007193702,0.00001015701,0.0003355214,0.00001991121,0.001407751,0.9909648,0.00005886734,0.002667604,0.000002413625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879582,0.002240947,0.007210894,0.00006959245,0.00001998595,0.00003345243,0.0003195408,0.0001892011,0.001958127],"genre_scores_gemma":[0.9931379,0.0006268688,0.002602881,0.00003931126,0.000006766777,0.00002862758,0.0006162153,0.00002239829,0.002919034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009105678,"threshold_uncertainty_score":0.003046215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01174288267802938,"score_gpt":0.2092532347407375,"score_spread":0.1975103520627082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}