{"id":"W2530152170","doi":"10.1182/blood.v120.21.1638.1638","title":"CSF1R Inhibition by PLX3397 in Patients with Relapsed or Refractory Hodgkin Lymphoma: Results From a Phase 2 Single Agent Clinical Trial","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Internal medicine; Gastroenterology; Lymphoma; Leukopenia; Refractory (planetary science); Anemia; Progression-free survival; Clinical endpoint; Adverse effect; Transplantation; Clinical trial; Surgery; Oncology; Toxicity; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001913423,0.001380008,0.00215332,0.0003309525,0.000323376,0.0008990339,0.0007678629,0.00141734,0.003418088],"category_scores_gemma":[0.0008769133,0.0004515708,0.001199636,0.0003746697,0.0006580192,0.0008816503,0.0002835087,0.002277002,0.0007162341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000575882,"about_ca_system_score_gemma":0.0009143915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004389659,"about_ca_topic_score_gemma":0.001009777,"domain_scores_codex":[0.9996521,0.0001754072,0.000023429,0.00004541431,0.00003002868,0.00007357297],"domain_scores_gemma":[0.9994289,0.0001421924,0.0001132332,0.00004757,0.00003917815,0.0002288477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8134199,0.04280403,0.004820557,0.001576016,0.002159479,0.0004686334,0.0004123585,0.0020232,0.02697486,0.000228672,0.004272178,0.1008402],"study_design_scores_gemma":[0.7631592,0.2258957,0.006453929,0.00005081787,0.000503037,0.0002086857,0.00004909899,0.0007755469,0.00139753,0.0001039516,0.00137631,0.00002620584],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937231,0.002834609,0.0002770733,0.0003307406,0.00007701807,0.001370024,0.0006018409,0.00007034317,0.0007152772],"genre_scores_gemma":[0.9897633,0.002917476,0.0008695814,0.0009101171,0.0001978617,0.002463005,0.001463582,0.00002323205,0.001391862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003418088,"threshold_uncertainty_score":0.01143461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04885471872648443,"score_gpt":0.3190104074154474,"score_spread":0.2701556886889629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}