{"id":"W2530306381","doi":"10.1182/blood.v124.21.777.777","title":"Dose Dependent Role of Gfi1 in Human MDS and AML and Its Suitability As a Novel Target","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Blood disorders and treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Myeloid leukemia; Cancer research; Haematopoiesis; Bone marrow; Stem cell; Myeloid; Transcription factor; Leukemia; Medicine; Biology; Immunology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001350145,0.0001697188,0.0001709324,0.0002653866,0.00009729282,0.0001498823,0.000131705,0.000184878,0.001279654],"category_scores_gemma":[0.0001206312,0.00008213091,0.000162307,0.0001611095,0.0001433942,0.00007513069,0.0001089294,0.000385212,0.000321314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002497737,"about_ca_system_score_gemma":0.0001517649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005051016,"about_ca_topic_score_gemma":0.0005083896,"domain_scores_codex":[0.9999139,0.00001779498,0.000006313824,0.00001853281,0.00002823516,0.00001520953],"domain_scores_gemma":[0.9999411,0.00001846317,0.00001238973,0.000007164608,0.000007960611,0.00001283239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002117897,0.00003681371,0.0003404531,0.00003124246,0.000003906755,0.00002461079,0.000008891551,0.0001012145,0.9970748,0.00004609936,0.00006853552,0.002051519],"study_design_scores_gemma":[0.00002525607,0.0008102586,0.00597922,0.000004533236,0.00001747946,0.000271657,0.0000155977,0.0005486867,0.9884014,0.00004307973,0.003879166,0.000003706297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921123,0.00314839,0.001889932,0.0001747896,0.00003117446,0.00006853467,0.001053941,0.00008027124,0.00144058],"genre_scores_gemma":[0.9926701,0.0009722828,0.002253637,0.00004919713,0.00001116305,0.00007503949,0.001498272,0.00001547776,0.002454833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001279654,"threshold_uncertainty_score":0.004280865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004985169714467528,"score_gpt":0.2278408405924209,"score_spread":0.2228556708779534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}