{"id":"W2530343061","doi":"10.1182/blood.v106.11.3598.3598","title":"Control of Oxidant-Stress and Inflammation by Iron Chelators Deferasirox (ICL670) or Deferoxamine in β-Thalassemia: An Ancillary Study of the Novartis CICL670A0107 Trial.","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Deferasirox; Deferoxamine; Medicine; Lipid peroxidation; Deferiprone; Malondialdehyde; Internal medicine; Gastroenterology; Thalassemia; Oxidative stress; Ferritin; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002432985,0.0008395267,0.001650199,0.0002063164,0.0002909817,0.0007058064,0.0005151041,0.0009531039,0.002145159],"category_scores_gemma":[0.001286099,0.0003656723,0.001004225,0.0002026085,0.0005655573,0.0003912648,0.0003050364,0.001526923,0.0002904166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005488317,"about_ca_system_score_gemma":0.0007750312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00081934,"about_ca_topic_score_gemma":0.001697865,"domain_scores_codex":[0.9991043,0.0006067932,0.00004780642,0.00008408054,0.00005728843,0.00009971175],"domain_scores_gemma":[0.9988515,0.0002834883,0.000276613,0.0001026104,0.00006342344,0.0004223089],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9640998,0.006120381,0.006133274,0.0004180671,0.001617277,0.00006493457,0.00005417276,0.000145514,0.004832535,0.0000676476,0.0005470817,0.01589926],"study_design_scores_gemma":[0.7100042,0.2508928,0.03345586,0.00008929427,0.002058408,0.0001665053,0.00005754461,0.0004229477,0.001418289,0.0001009901,0.001308404,0.00002482783],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947277,0.003927005,0.00009689308,0.0002072765,0.00006915673,0.0002693377,0.0002183659,0.00001145228,0.0004728104],"genre_scores_gemma":[0.9968882,0.001071782,0.0002820507,0.0003661177,0.0001816205,0.0002528894,0.0005147074,0.000003250649,0.0004394007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002432985,"threshold_uncertainty_score":0.01286703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00834937162590162,"score_gpt":0.2349001647967654,"score_spread":0.2265507931708637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}