{"id":"W2530476023","doi":"10.1002/aic.15544","title":"Reaction engineering with enzymes: A relatively uncharted territory","year":2016,"lang":"en","type":"article","venue":"AIChE Journal","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Toronto; National Science Foundation","keywords":"Candida antarctica; Transesterification; Chemical reaction engineering; Kinetics; Chemistry; Work (physics); Lipase; Acrylate; Chemical kinetics; Organic chemistry; Thermodynamics; Enzyme; Catalysis; Chemical engineering; Polymer; Copolymer; Engineering; Physics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004096776,0.0008224341,0.001323951,0.0009829346,0.0008593067,0.004006572,0.00123727,0.001973822,0.002213917],"category_scores_gemma":[0.004051202,0.0006569095,0.000638665,0.001392448,0.005720784,0.01249716,0.002432758,0.003179113,0.002004775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001946875,"about_ca_system_score_gemma":0.001132429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005432552,"about_ca_topic_score_gemma":0.0003753318,"domain_scores_codex":[0.9982764,0.0004471643,0.0001424792,0.0004651008,0.0005107916,0.0001581158],"domain_scores_gemma":[0.9976279,0.001603521,0.0001277985,0.0002937576,0.0002288934,0.0001180454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001976822,0.0003566024,0.001135355,0.003066376,0.00008545384,0.0004265905,0.001097772,0.004455314,0.06126605,0.3714162,0.00686787,0.5496288],"study_design_scores_gemma":[0.00004277803,0.0006133751,0.0005346594,0.0007903608,0.00005252914,0.001148519,0.0005125317,0.003647688,0.06831493,0.1506229,0.7736018,0.0001179132],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.03527921,0.7542391,0.1540293,0.02138271,0.002026917,0.00009389063,0.0001310829,0.0005276136,0.03229026],"genre_scores_gemma":[0.1776259,0.7308898,0.06160598,0.004896133,0.00258684,0.0001943634,0.0002661897,0.0004026258,0.02153211],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004096776,"threshold_uncertainty_score":0.02166611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005701118956991871,"score_gpt":0.1999389747466026,"score_spread":0.1942378557896107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}