{"id":"W2530494618","doi":"10.1164/rccm.201601-0083oc","title":"A Multicenter Randomized Trial Assessing the Efficacy of Helium/Oxygen in Severe Exacerbations of Chronic Obstructive Pulmonary Disease","year":2016,"lang":"en","type":"article","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Respiratory Support and Mechanisms","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Medicine; Heliox; COPD; Anesthesia; Respiratory failure; Hypercapnia; Ventilation (architecture); Clinical endpoint; Work of breathing; Intubation; Intensive care; Randomized controlled trial; Mechanical ventilation; Intensive care medicine; Internal medicine; Acidosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001103271,0.0001753229,0.0011231,0.0002399654,0.00005049838,0.000005451351,0.0001269504,0.00004852811,0.0001282635],"category_scores_gemma":[0.004215172,0.00008365532,0.0002346214,0.000255336,0.002296537,0.0001620098,0.0000346582,0.0002542182,4.523455e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008548078,"about_ca_system_score_gemma":0.0005370846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001055285,"about_ca_topic_score_gemma":0.000001714996,"domain_scores_codex":[0.9973877,0.0006001946,0.001079654,0.0001828731,0.0005299569,0.0002196116],"domain_scores_gemma":[0.9960604,0.002285768,0.0004804047,0.0002433745,0.000592733,0.0003373469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6167536,0.0007008055,0.032722,0.0006932486,0.0002680299,0.0007030331,0.002762963,0.000003946604,0.04240844,0.001265859,0.00006412616,0.301654],"study_design_scores_gemma":[0.8677711,0.01226541,0.08361602,0.004685693,0.002079812,0.000187291,0.02279129,0.00003741613,0.003392802,0.0005873018,0.002266642,0.0003191645],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901743,0.005712003,0.0009909838,0.002037543,0.00028251,0.0005701336,0.000009559668,0.000004854303,0.0002181465],"genre_scores_gemma":[0.9986904,0.00009277042,0.0001400075,0.0004888807,0.0005413787,0.00001529094,0.00000109214,0.00001628172,0.00001395238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3013348,"threshold_uncertainty_score":0.8461687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01915560233029176,"score_gpt":0.3317858893109048,"score_spread":0.312630286980613,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}