{"id":"W2530522766","doi":"10.1039/c6ay02190e","title":"In vitro physiological performance factors of a catalase-based biosensor for real-time electrochemical detection of brain hydrogen peroxide in freely-moving animals","year":2016,"lang":"en","type":"article","venue":"Analytical Methods","topic":"Electrochemical sensors and biosensors","field":"Engineering","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"NeuroRx Research (Canada)","funders":"Higher Education Authority","keywords":"Hydrogen peroxide; Neurochemical; Catalase; Biosensor; Chemistry; In vitro; Electrochemistry; Chromatography; Biochemistry; Combinatorial chemistry; Enzyme; Biology; Neuroscience; Electrode","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006483451,0.0005366361,0.0001989715,0.0002404858,0.0001063111,0.0002252556,0.0004627485,0.0004530926,0.001203393],"category_scores_gemma":[0.0007071128,0.0002428892,0.0002482871,0.0001723565,0.0001974264,0.0002779923,0.0001517601,0.000535768,0.0003711159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004306634,"about_ca_system_score_gemma":0.0002480595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001230542,"about_ca_topic_score_gemma":0.0009740136,"domain_scores_codex":[0.9997382,0.00005848785,0.00002696805,0.00005335878,0.00007275406,0.00005035246],"domain_scores_gemma":[0.9997284,0.0001218701,0.00004752969,0.00002207004,0.00004597225,0.00003406244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001010186,0.00001573436,0.0000808761,0.00002825006,0.000004723347,0.00001935704,0.0000100596,0.00006485303,0.9987885,0.00002860199,0.00004102883,0.0008169801],"study_design_scores_gemma":[0.000004071625,0.0002160983,0.0009806353,0.000002627523,0.000007893774,0.00004944286,0.000006994549,0.0003852761,0.9980118,0.00001626041,0.0003155816,0.000003329397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9556075,0.004808951,0.0361414,0.0003200647,0.0001305462,0.0000703992,0.0006449713,0.0002429308,0.002033195],"genre_scores_gemma":[0.9773797,0.002281395,0.01532081,0.0001233166,0.00003307194,0.0001173898,0.001577339,0.00004642874,0.003120481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001230542,"threshold_uncertainty_score":0.004025757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01732741469496639,"score_gpt":0.2860744610143635,"score_spread":0.2687470463193971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}