{"id":"W2530985076","doi":"10.1093/ecco-jcc/jjw178","title":"Characterisation of Mucosal Healing with Adalimumab Treatment in Patients with Moderately to Severely Active Crohn’s Disease: Results from the EXTEND Trial","year":2016,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster University Medical Centre","funders":"AbbVie; Abbott Laboratories","keywords":"Gastroenterology; Medicine; Transverse colon; Ileum; Internal medicine; Adalimumab; Crohn's disease; Rectum; Sigmoid colon; Colonoscopy; Placebo; Disease; Colorectal cancer; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008965962,0.0001138538,0.0001601993,0.00003002894,0.00004424062,0.00002390501,0.0000672121,0.00003861715,0.000005753633],"category_scores_gemma":[0.00005806437,0.00005639551,0.00004280953,0.00002919534,0.00004744484,0.00001944486,0.00001884894,0.00003487775,3.107358e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005129398,"about_ca_system_score_gemma":0.0002539388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007835811,"about_ca_topic_score_gemma":0.0002010737,"domain_scores_codex":[0.999151,0.00008773041,0.0003022422,0.000151146,0.0001800095,0.0001279081],"domain_scores_gemma":[0.9991351,0.00003121869,0.0003600552,0.0001441514,0.0001963796,0.0001330762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9817446,0.0002279696,0.006800009,0.000005400616,0.0001152778,0.0001365136,0.0003414127,0.00003429562,0.0001365199,0.00001097362,0.00004930984,0.01039766],"study_design_scores_gemma":[0.02810818,0.001361291,0.9688783,0.0001201533,0.00004774937,0.000002338462,0.00005885997,0.000003898895,0.001026203,0.00003266192,0.0002718458,0.00008849914],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984986,0.00003613651,0.00007669961,0.0002962881,0.00004901111,0.0003822551,0.0006385173,0.00000111403,0.00002142297],"genre_scores_gemma":[0.9995384,0.00005091195,0.00007115361,0.00007803517,0.0001686063,0.00001461623,0.00003029403,0.0000109572,0.00003701928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9620783,"threshold_uncertainty_score":0.2299742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008799915654701576,"score_gpt":0.2291928004538883,"score_spread":0.2203928847991867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}