{"id":"W2531142387","doi":"10.1213/ane.0000000000001655","title":"Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor: A Biased-Coin Up-and-Down Sequential Allocation Trial to Determine the Optimum Interval Time Between Boluses of a Fixed Volume of 10 mL of Bupivacaine 0.0625% With Fentanyl 2 μg/mL","year":2016,"lang":"en","type":"article","venue":"Anesthesia & Analgesia","topic":"Anesthesia and Pain Management","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Medicine; Fentanyl; Bupivacaine; Anesthesia; Bolus (digestion); Regimen; Loading dose; Local anesthetic; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00371321,0.00183022,0.00427444,0.000790053,0.0004155217,0.0009530871,0.001155284,0.002568911,0.003462772],"category_scores_gemma":[0.006918385,0.0008825079,0.001140505,0.0005459103,0.002049492,0.0009805037,0.0006974706,0.001908656,0.0005065674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007531318,"about_ca_system_score_gemma":0.001838937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004293206,"about_ca_topic_score_gemma":0.00044414,"domain_scores_codex":[0.996988,0.002042682,0.0001964413,0.0003349738,0.0002040569,0.0002337925],"domain_scores_gemma":[0.9965887,0.001778521,0.0007050758,0.0002803646,0.000143093,0.0005042634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9720833,0.009397928,0.0002426557,0.0006796729,0.0002294335,0.00002704997,0.00004943417,0.0005902179,0.003138057,0.00026662,0.0001501296,0.01314549],"study_design_scores_gemma":[0.8786899,0.118369,0.0004205779,0.00004814579,0.0001982149,0.00001942791,0.000008739666,0.001113497,0.0006704383,0.000231048,0.0002170685,0.00001402986],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789629,0.003069186,0.003240068,0.0005173041,0.0008013573,0.01202944,0.0002191596,0.00009649534,0.001063999],"genre_scores_gemma":[0.9696035,0.001549569,0.008301141,0.0007460546,0.000730291,0.01772217,0.0002191771,0.00002127264,0.001106829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00427444,"threshold_uncertainty_score":0.01963753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02329378168793941,"score_gpt":0.2672382768479362,"score_spread":0.2439444951599967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}