{"id":"W2531142387","doi":"10.1213/ane.0000000000001655","title":"Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor: A Biased-Coin Up-and-Down Sequential Allocation Trial to Determine the Optimum Interval Time Between Boluses of a Fixed Volume of 10 mL of Bupivacaine 0.0625% With Fentanyl 2 μg/mL","year":2016,"lang":"en","type":"article","venue":"Anesthesia & Analgesia","topic":"Anesthesia and Pain Management","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Medicine; Fentanyl; Bupivacaine; Anesthesia; Bolus (digestion); Regimen; Loading dose; Local anesthetic; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001198752,0.0004555662,0.001413741,0.0004168327,0.00009328115,0.00002141063,0.000462565,0.0001576627,0.0001912256],"category_scores_gemma":[0.0002472503,0.0002861629,0.0003663024,0.0006071521,0.0004520364,0.0001600833,0.00008774897,0.0001210633,0.000005849321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009358924,"about_ca_system_score_gemma":0.0001866714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003705389,"about_ca_topic_score_gemma":0.0001114383,"domain_scores_codex":[0.9965478,0.0002696128,0.001433044,0.0005746715,0.000652979,0.0005219294],"domain_scores_gemma":[0.9968149,0.0004663552,0.001093476,0.000839387,0.0005651003,0.0002207891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2005776,0.002304068,0.6855359,0.006871003,0.003767182,0.0003785589,0.004778365,0.00008969623,0.05984306,0.0007132316,0.002941237,0.0322001],"study_design_scores_gemma":[0.04656275,0.01437424,0.8587217,0.002953788,0.002534128,0.0001678479,0.001022426,0.001214597,0.06443078,0.00003504497,0.007210426,0.0007723032],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862652,0.0001343337,0.0009985594,0.009338921,0.00001786625,0.00314263,0.0000467976,0.00004581938,0.000009828593],"genre_scores_gemma":[0.9944147,0.00004651992,0.00194246,0.0002406465,0.0001441405,0.0002338028,0.00007178992,0.00007443469,0.002831489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1731858,"threshold_uncertainty_score":0.9999591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02329378168793941,"score_gpt":0.2672382768479362,"score_spread":0.2439444951599967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}