{"id":"W2531249461","doi":"10.1016/j.celrep.2016.09.085","title":"A Metabolic Roadblock in Inflammatory Macrophages","year":2016,"lang":"en","type":"letter","venue":"Cell Reports","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Inflammation; Macrophage; Biology; Immunology; Chemistry; Microbiology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0004470528,0.0005633792,0.0008666838,0.0003907969,0.00008195746,0.00002709137,0.0004000882,0.002337414,0.003925301],"category_scores_gemma":[0.00006745408,0.0004603813,0.0002769406,0.0001283825,0.0003193618,0.00007832491,0.0002590341,0.002422973,0.002257884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001545062,"about_ca_system_score_gemma":0.000362411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008155245,"about_ca_topic_score_gemma":0.000006458418,"domain_scores_codex":[0.9966472,0.0003027274,0.001068906,0.0009112252,0.00009779473,0.0009721268],"domain_scores_gemma":[0.9974458,0.0001608564,0.0008215543,0.001469812,0.00008485532,0.00001715069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001247794,0.0000186745,0.001020926,0.0001280039,0.0001051421,0.01091785,0.0000947709,7.168775e-7,0.08047663,0.00000233018,0.904822,0.002400492],"study_design_scores_gemma":[0.0004042052,0.0000158219,0.0003885342,0.0001324155,0.00006071198,0.0009153683,0.000005307659,1.897799e-8,0.17098,0.0001302098,0.8265181,0.0004493259],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.08679388,0.4592724,0.00002898299,0.2031895,0.06221274,0.003371353,0.0001253845,0.0008634016,0.1841424],"genre_scores_gemma":[0.0464992,0.002671062,0.00005735682,0.2651926,0.003686685,0.0004478211,0.0006933506,0.0003777127,0.6803742],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.4962318,"threshold_uncertainty_score":0.9998785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006794919304244325,"score_gpt":0.2132601933240909,"score_spread":0.2064652740198465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}