{"id":"W2531443355","doi":"10.1128/iai.00692-16","title":"Dynamic Interactions of a Conserved Enterotoxigenic Escherichia coli Adhesin with Intestinal Mucins Govern Epithelium Engagement and Toxin Delivery","year":2016,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs; CH.I.L.D. Foundation; Government of Canada; National Institutes of Health; Tulane University","keywords":"Bacterial adhesin; Enterotoxigenic Escherichia coli; Mucin; Biology; Microbiology; Toxin; Escherichia coli; Epithelium; Intestinal epithelium; Mucin 2; Enterotoxin; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001591032,0.0001670532,0.0000971206,0.00008686906,0.0001015859,0.0002928687,0.0001238781,0.000193596,0.0004132288],"category_scores_gemma":[0.0001499197,0.00009922423,0.00008995024,0.00009769342,0.0002107578,0.0002894737,0.000216655,0.0002571645,0.0001384598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003141617,"about_ca_system_score_gemma":0.0001675308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004038918,"about_ca_topic_score_gemma":0.0005324731,"domain_scores_codex":[0.9999092,0.00001983343,0.000004443143,0.00001549882,0.00001942218,0.00003160035],"domain_scores_gemma":[0.9999423,0.00001096492,0.00002125129,0.000005456108,0.000006819881,0.00001322276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000202797,0.000007163484,0.0004390852,0.00001078216,0.000001195632,0.00004258924,0.0000123766,0.00009023506,0.9983151,0.0003053195,0.00001274748,0.0007431284],"study_design_scores_gemma":[0.000008655603,0.0001956106,0.01749909,0.000007691012,0.000008618414,0.0003229139,0.0001092463,0.003739335,0.9749097,0.0002878617,0.002905121,0.000006270238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936963,0.0006873531,0.004445822,0.0001227999,0.000006849993,0.00001010142,0.00002573785,0.0000164998,0.0009885343],"genre_scores_gemma":[0.9973795,0.0004634906,0.00131359,0.00002323017,0.000002297573,0.000005249936,0.00002406928,0.000004646508,0.0007838422],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004132288,"threshold_uncertainty_score":0.002279401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01754926280888258,"score_gpt":0.2709968805475176,"score_spread":0.253447617738635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}