{"id":"W2531660572","doi":"10.1038/ng.3688","title":"The genomic landscape of schwannoma","year":2016,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Neurofibromatosis and Schwannoma Cases","field":"Medicine","cited_by":188,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children; Princess Margaret Cancer Centre; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cancer research; Carcinogenesis; Fusion gene; Exome; DNA methylation; Exome sequencing; Schwannoma; MAPK/ERK pathway; Genetics; Mutation; Gene; Pathology; Gene expression; Signal transduction; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009518303,0.0000882818,0.0001450691,0.00003594928,0.00006021727,0.000009631547,0.0001240127,0.0001411359,0.00004361666],"category_scores_gemma":[0.00009510285,0.00004001457,0.00008110954,0.00009001003,0.0000811319,0.00001180828,0.00004856713,0.0001480975,0.00002759541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009458246,"about_ca_system_score_gemma":0.00006679347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":3.745951e-7,"about_ca_topic_score_gemma":0.000001308563,"domain_scores_codex":[0.9993007,0.00002043907,0.0001838355,0.0001414375,0.0001913458,0.0001622956],"domain_scores_gemma":[0.9992399,0.0001254589,0.00006952831,0.0003993283,0.00009890163,0.00006689758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003880694,0.00009734857,0.2560396,0.0000671707,0.0001165022,0.0001015199,0.00005367121,8.421106e-7,0.6423089,0.001929942,0.0404774,0.05841906],"study_design_scores_gemma":[0.001323758,0.0004875491,0.5499282,0.00008423592,0.00007275407,0.0002949677,0.00003246019,0.00001842437,0.2190972,0.0003638555,0.2281687,0.0001278687],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863182,0.008968048,0.00001242415,0.00172489,0.0002667011,0.0001298268,0.00001809262,0.00002071259,0.002541099],"genre_scores_gemma":[0.9977084,0.0005033743,0.0005301205,0.0001921782,0.0001953384,0.000003114417,0.000001808756,0.000017103,0.0008485016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4232117,"threshold_uncertainty_score":0.1631747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009866244668198375,"score_gpt":0.2521280174606437,"score_spread":0.2422617727924453,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}