{"id":"W2531691490","doi":"10.1093/ofid/ofw217","title":"Parasite Clearance and Artemether Pharmacokinetics Parameters Over the Course of Artemether-Lumefantrine Treatment for Malaria in Human Immunodeficiency Virus (HIV)-Infected and HIV-Uninfected Ugandan Children","year":2016,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Malaria Research and Control","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; National Institute of Child Health and Human Development; International Development Research Centre","keywords":"Artemether; Medicine; Artemether/lumefantrine; Lumefantrine; Dihydroartemisinin; Lopinavir; Nevirapine; Ritonavir; Artemisinin; Dosing; Pharmacokinetics; Efavirenz; Pharmacology; Virology; Malaria; Immunology; Viral load; Human immunodeficiency virus (HIV); Plasmodium falciparum; Antiretroviral therapy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002834928,0.0003053886,0.0005788557,0.0001440336,0.0002280422,0.0001023065,0.0001753778,0.00007816524,0.0002004521],"category_scores_gemma":[0.0001633923,0.0001726908,0.0001314264,0.0002418582,0.0003349456,0.0001948057,0.0001283924,0.0001155893,0.000004710959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007774597,"about_ca_system_score_gemma":0.0001178391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006314751,"about_ca_topic_score_gemma":0.0002802149,"domain_scores_codex":[0.9982471,0.0002087725,0.0003977774,0.0004250186,0.0002049953,0.0005163673],"domain_scores_gemma":[0.998679,0.0003737645,0.0001878703,0.0004377138,0.0001129684,0.0002086879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002049822,0.001427711,0.9524028,0.00004358621,0.0005645879,0.000009623348,0.00009277344,0.00001115009,0.01848837,0.001275885,0.0003598653,0.02327377],"study_design_scores_gemma":[0.02143804,0.001868177,0.971425,0.0001496557,0.0004379719,0.00003251561,0.00003909986,0.0004234402,0.002636296,0.0005992707,0.0007151666,0.0002353906],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923458,0.001132352,0.0003665242,0.001634486,0.00004304848,0.003602752,0.0004522137,0.00004348092,0.0003794098],"genre_scores_gemma":[0.9982526,0.0006219531,0.0000324787,0.0001893797,0.00002938344,0.0004347888,0.00005193235,0.00004286215,0.000344669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02303838,"threshold_uncertainty_score":0.7042125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01296423258157637,"score_gpt":0.317942888692564,"score_spread":0.3049786561109876,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}