{"id":"W2531711809","doi":"10.1182/blood.v120.21.3625.3625","title":"SL-401, A Targeted Therapy Directed to the Interleukin-3 Receptor Present On Leukemia Blasts and Cancer Stem Cells, Is Active As a Single Agent in Patients with Advanced AML","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Internal medicine; Oncology; Leukemia; Stem cell; Cancer; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003021311,0.0002804339,0.0006205749,0.0002507001,0.00017363,0.0002165529,0.0001633028,0.0001842322,0.001042529],"category_scores_gemma":[0.0002732125,0.0001248744,0.0001891392,0.0002002161,0.0002269914,0.0002015115,0.0001624403,0.0003620466,0.0001913056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002998824,"about_ca_system_score_gemma":0.0004455744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003193531,"about_ca_topic_score_gemma":0.0008978383,"domain_scores_codex":[0.9998972,0.00003008653,0.000008445313,0.00002036049,0.00002017329,0.0000237293],"domain_scores_gemma":[0.999795,0.00003665161,0.00005087379,0.000009934984,0.000007798832,0.00009980553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1222738,0.01166487,0.2249476,0.0004627643,0.0004458286,0.001659893,0.000495689,0.003282157,0.3147534,0.0004224814,0.00281746,0.3167741],"study_design_scores_gemma":[0.05525013,0.3519144,0.5049569,0.0000704226,0.0007840023,0.004526203,0.0002090161,0.006399267,0.06246668,0.0003783061,0.01299407,0.00005055866],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989291,0.0004786589,0.00009598977,0.00003896076,0.000004879041,0.0000483885,0.00006059284,0.00001451593,0.0003288953],"genre_scores_gemma":[0.9988574,0.0002699462,0.000329667,0.00006428493,0.00002365844,0.00004861156,0.0002059243,0.000001799106,0.0001987579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001042529,"threshold_uncertainty_score":0.003487587,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01839835924368352,"score_gpt":0.2754945196894453,"score_spread":0.2570961604457618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}