{"id":"W2531856440","doi":"10.1161/hypertensionaha.116.07859","title":"Extent of Vascular Remodeling Is Dependent on the Balance Between Estrogen Receptor α and G-Protein–Coupled Estrogen Receptor","year":2016,"lang":"en","type":"article","venue":"Hypertension","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland; Western University","funders":"","keywords":"GPER; Estrogen receptor; Downregulation and upregulation; Vascular smooth muscle; Endocrinology; Estrogen; Internal medicine; Receptor; Biology; Estrogen receptor beta; Cell biology; Chemistry; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000342976,0.0002647263,0.0002680483,0.0002756394,0.0001445624,0.0003855842,0.000124609,0.0002412116,0.0008168684],"category_scores_gemma":[0.000238075,0.0002100445,0.0001991748,0.0001578302,0.0002717527,0.0002951172,0.0001368098,0.0005127733,0.0002150798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000168879,"about_ca_system_score_gemma":0.0001387946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001555368,"about_ca_topic_score_gemma":0.000235712,"domain_scores_codex":[0.9998142,0.00004584778,0.00001619509,0.00004008334,0.00004550431,0.00003814361],"domain_scores_gemma":[0.9996705,0.00006620518,0.0001281752,0.00003336494,0.00003954182,0.00006214515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001741061,0.00004780158,0.001383836,0.00003727889,0.00001067741,0.0000906594,0.00002431013,0.00003463291,0.992699,0.0001172104,0.00002995609,0.005350726],"study_design_scores_gemma":[0.00006800386,0.002549958,0.2388419,0.00004462423,0.0001059437,0.001497163,0.0002310303,0.0007134705,0.7505223,0.0005724368,0.004830305,0.0000229641],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807069,0.010318,0.004880783,0.0002625737,0.00007395847,0.00003649166,0.0001249644,0.000107196,0.003489187],"genre_scores_gemma":[0.9909092,0.005389383,0.001557699,0.000103878,0.00004910546,0.00003455703,0.0001000653,0.000009564216,0.001846538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008168684,"threshold_uncertainty_score":0.002732754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01324541680071869,"score_gpt":0.2128973908780253,"score_spread":0.1996519740773066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}