{"id":"W2531893716","doi":"10.1021/jacs.6b08906","title":"Ambient Decarboxylative Arylation of Malonate Half-Esters via Oxidative Catalysis","year":2016,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; University of Alberta","keywords":"Chemistry; Reactivity (psychology); Electrophile; Malonate; Decarboxylation; Malonic acid; Catalysis; Nucleophile; Oxidative phosphorylation; Oxidative decarboxylation; Combinatorial chemistry; Organic chemistry; Medicinal chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002176052,0.0007522308,0.0001971249,0.0002024693,0.0001941119,0.000339083,0.0003960923,0.0002400263,0.00144387],"category_scores_gemma":[0.0001824689,0.0001540126,0.000180732,0.0001723425,0.000295652,0.0005745485,0.000616271,0.0005754132,0.0008118384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002511971,"about_ca_system_score_gemma":0.0003248432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004308932,"about_ca_topic_score_gemma":0.0008669816,"domain_scores_codex":[0.9998186,0.00001949281,0.00001716403,0.00004298222,0.00003311945,0.00006862122],"domain_scores_gemma":[0.9999205,0.000008624649,0.00002528626,0.00001389696,0.00001350813,0.00001829862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000207582,0.00007502588,0.0004519406,0.0002279962,0.00002236743,0.0003725408,0.0001945606,0.0004571208,0.9757015,0.003672561,0.0004311088,0.01818571],"study_design_scores_gemma":[0.000009362564,0.0001799789,0.0002723176,0.000005010904,0.00000914296,0.0001440952,0.00001880443,0.0003867969,0.9926007,0.0001456994,0.006217827,0.00001030498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9394248,0.00447284,0.03737359,0.0003400225,0.0002008397,0.00008022913,0.0004331416,0.0003993223,0.01727515],"genre_scores_gemma":[0.990875,0.002024516,0.004239651,0.00005461677,0.00002730319,0.00001689901,0.0001837117,0.00003837009,0.002539798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00144387,"threshold_uncertainty_score":0.004830182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01297002208157088,"score_gpt":0.2717485809635632,"score_spread":0.2587785588819924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}