{"id":"W2531900397","doi":"10.1126/scisignal.aak9385","title":"Oxidant signaling underlies PKGIα modulation of Ca <sup>2+</sup> sparks and BK <sub>Ca</sub> in myogenically active arterioles","year":2016,"lang":"en","type":"letter","venue":"Science Signaling","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Cell biology; Chemistry; Signal transduction; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007608628,0.0003510187,0.000571035,0.000220684,0.0009848671,0.001098887,0.0005630277,0.009216174,0.003611469],"category_scores_gemma":[0.001937077,0.0002424019,0.0004954946,0.0001558704,0.001577526,0.001273926,0.0005035602,0.009269361,0.002633693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009562534,"about_ca_system_score_gemma":0.0004132373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002588681,"about_ca_topic_score_gemma":0.0005149316,"domain_scores_codex":[0.9996749,0.00005874095,0.00005689075,0.00005139317,0.00009721482,0.00006086531],"domain_scores_gemma":[0.999233,0.0003562186,0.0001175889,0.00006053779,0.0001266088,0.0001060113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003998841,0.0005678327,0.006243986,0.0009443539,0.0001099183,0.04941905,0.0007112003,0.0004273641,0.0590655,0.03179249,0.6993051,0.1474144],"study_design_scores_gemma":[0.001579438,0.001145888,0.01178556,0.0003427455,0.0001397927,0.04570134,0.0007333301,0.003175615,0.04469653,0.0589032,0.8316543,0.0001422086],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.0311466,0.02367879,0.001768369,0.8802031,0.05000247,0.00007226244,0.0002225413,0.0002056521,0.01270022],"genre_scores_gemma":[0.3737854,0.03498002,0.003506584,0.3429736,0.2173367,0.0002039804,0.0002316883,0.00005600767,0.02692606],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.009216174,"threshold_uncertainty_score":0.01208156,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0160871079761344,"score_gpt":0.2538668258414175,"score_spread":0.2377797178652831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}