{"id":"W2531915249","doi":"10.1038/ncomms13134","title":"The solution structure of an anti-CRISPR protein","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Computational biology; Biology; DNA; ENCODE; Trans-activating crRNA; Gene; Pseudomonas aeruginosa; Genetics; Cas9; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000833565,0.0002796622,0.0002497137,0.000144193,0.000454207,0.0004801583,0.0006141549,0.0006020881,0.001903979],"category_scores_gemma":[0.0001947455,0.0002355608,0.000282713,0.0002094058,0.0003071106,0.0003251567,0.0002247907,0.001369176,0.0008443749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008719937,"about_ca_system_score_gemma":0.0007007906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001385975,"about_ca_topic_score_gemma":0.0009607491,"domain_scores_codex":[0.9999202,0.00001075568,0.000004048031,0.00002016163,0.00002822341,0.00001652855],"domain_scores_gemma":[0.99993,0.00001080691,0.00001214092,0.000007060049,0.0000175093,0.00002243522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002476918,0.0001690738,0.0006253248,0.0001592536,0.00002840615,0.0005620297,0.0001472476,0.01127981,0.9603118,0.01434119,0.002998953,0.009129227],"study_design_scores_gemma":[0.0001222974,0.0006571165,0.002222124,0.00002907284,0.00005028959,0.000740022,0.0001699797,0.05272436,0.869884,0.006906183,0.06640745,0.00008713568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9155203,0.00235231,0.05833248,0.003345566,0.0004847715,0.0001008642,0.001959781,0.0004416562,0.01746217],"genre_scores_gemma":[0.9201953,0.001828409,0.05842934,0.0007304756,0.00005686946,0.0001027441,0.004452481,0.00008280599,0.01412155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001903979,"threshold_uncertainty_score":0.006369472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006904017346852162,"score_gpt":0.3118007315586675,"score_spread":0.3048967142118154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}