{"id":"W2532035602","doi":"10.1111/imm.12682","title":"Detrimental effect of systemic antimicrobial <scp>CD</scp> 4 <sup>+</sup> T‐cell reactivity on gut epithelial integrity","year":2016,"lang":"en","type":"article","venue":"Immunology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; University of Bern; AbbVie","keywords":"Immune system; Antimicrobial peptides; Immunology; Microbiology; Antigen; Intestinal epithelium; Antimicrobial; Biology; Innate immune system; T cell; Beta defensin; Systemic inflammation; Inflammation; Epithelium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002231062,0.0003229296,0.0002592892,0.0001070285,0.00008984848,0.0002487606,0.0001100111,0.0002756116,0.002148467],"category_scores_gemma":[0.0001590142,0.00007922737,0.0001208908,0.00005760252,0.0002514549,0.0001304579,0.0001931371,0.0004930485,0.000307643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001360223,"about_ca_system_score_gemma":0.0001248218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001319691,"about_ca_topic_score_gemma":0.0001920833,"domain_scores_codex":[0.9997684,0.00008454528,0.000018879,0.00002818298,0.00004255544,0.0000574536],"domain_scores_gemma":[0.9997247,0.00009773317,0.00004821423,0.00004308993,0.00002851188,0.00005772073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002531868,0.00002817155,0.0003254321,0.00002918491,0.000002730112,0.00005907379,0.000004976483,0.00004401763,0.9985417,0.00002726364,0.00002367055,0.0006604824],"study_design_scores_gemma":[0.00001540808,0.001041375,0.004378064,0.000006503345,0.00001246553,0.000310565,0.0000306881,0.0004246029,0.9931235,0.00002956714,0.0006252482,0.000002118564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978774,0.00038039,0.0007666097,0.00004684142,0.00001519243,0.00001188729,0.00008174893,0.00002181951,0.0007981126],"genre_scores_gemma":[0.9977742,0.0001381534,0.0009237304,0.00005352978,0.00001123194,0.00002065789,0.000116936,0.000008481928,0.000953096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002148467,"threshold_uncertainty_score":0.007187366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007684380917696848,"score_gpt":0.2550376061139914,"score_spread":0.2473532251962945,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}