{"id":"W2532168152","doi":"10.1016/j.molcel.2016.09.002","title":"Tail and Kinase Modules Differently Regulate Core Mediator Recruitment and Function In Vivo","year":2016,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":138,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Mediator; Biology; RNA polymerase II; Coactivator; Cell biology; Promoter; Function (biology); Genetics; Gene; Transcription factor; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003690401,0.0003467025,0.0003076158,0.0002521581,0.0002893407,0.0009543261,0.0004988993,0.000416701,0.003400002],"category_scores_gemma":[0.0004371483,0.0004758124,0.0002978247,0.000163638,0.0003949903,0.0007435041,0.0006564426,0.0009239506,0.001201177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000488926,"about_ca_system_score_gemma":0.0002388683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003633723,"about_ca_topic_score_gemma":0.001148634,"domain_scores_codex":[0.9996852,0.00003403012,0.00001881005,0.0001049447,0.00005708911,0.0000999195],"domain_scores_gemma":[0.9996145,0.00009789328,0.00008007056,0.00005968264,0.00003403677,0.0001137746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002192561,0.0000106025,0.0002614973,0.00001130955,0.000004218291,0.00001146312,0.000006974718,0.00003787034,0.9984457,0.000308429,0.00002668097,0.0006561161],"study_design_scores_gemma":[0.0000222587,0.00003788486,0.007075792,0.000003280136,0.00001048251,0.0001007207,0.00002121669,0.001085776,0.990498,0.000175932,0.0009623301,0.000006247083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902238,0.001280354,0.005980618,0.0001045001,0.00005968291,0.00001253153,0.0003046653,0.000124771,0.001909049],"genre_scores_gemma":[0.9938534,0.0002950481,0.001689882,0.0001046771,0.00001069518,0.00001370271,0.0004775355,0.0001222418,0.003432911],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003400002,"threshold_uncertainty_score":0.01137412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01055339288845378,"score_gpt":0.2067813626218398,"score_spread":0.196227969733386,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}