{"id":"W2532290530","doi":"10.1200/jco.2006.24.18_suppl.10627","title":"Pegylated liposomal doxorubicin (PLD) with cyclophosphamide (C) as 1<sup>st</sup>-line chemotherapy for metastatic breast cancer (MBC) patients previously treated with adjuvant anthracyclines","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame; Queen Elizabeth II Health Sciences Centre","funders":"","keywords":"Medicine; Cardiotoxicity; Metastatic breast cancer; Anthracycline; Internal medicine; Doxorubicin; Cyclophosphamide; Epirubicin; Mucositis; Gastroenterology; Oncology; Chemotherapy; Neutropenia; Adjuvant; Regimen; Breast cancer; Febrile neutropenia; Discontinuation; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004805058,0.0003611069,0.0005618797,0.0002057114,0.0002203482,0.0004100392,0.0003025381,0.0003462878,0.002135495],"category_scores_gemma":[0.0002843178,0.0002173487,0.0002404287,0.0002727817,0.0004224404,0.0003639927,0.0003854217,0.0005691981,0.0004703375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004568051,"about_ca_system_score_gemma":0.0005842464,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003719031,"about_ca_topic_score_gemma":0.000804716,"domain_scores_codex":[0.9998617,0.00004321185,0.00001311095,0.00002763961,0.0000168039,0.00003754583],"domain_scores_gemma":[0.9997939,0.00002483297,0.00003184331,0.00001636417,0.000007425993,0.0001256919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.3011029,0.04045977,0.02997373,0.001297825,0.0006225243,0.0009431898,0.0005361704,0.008873258,0.3398148,0.001020611,0.004966551,0.2703887],"study_design_scores_gemma":[0.2020672,0.5850435,0.0871322,0.0002113947,0.0006471013,0.002340711,0.0001441504,0.01126428,0.09201844,0.0003879906,0.01864482,0.00009816854],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973431,0.0008512425,0.0003058474,0.0001006267,0.00002788035,0.0004524682,0.0001113656,0.00003220431,0.0007752071],"genre_scores_gemma":[0.9973822,0.0004220512,0.0008397257,0.0001121875,0.00002764542,0.0003531103,0.0003221791,0.000004487878,0.0005364021],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002135495,"threshold_uncertainty_score":0.007143915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04225070822638877,"score_gpt":0.4239758659361589,"score_spread":0.3817251577097701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}