{"id":"W2532575009","doi":"10.1039/c6ob01484d","title":"Design, synthesis, and biological evaluation of CXCR4 ligands","year":2016,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; Université de Sherbrooke","funders":"","keywords":"Chemistry; Combinatorial chemistry; Computational biology; Nanotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003852388,0.0003502333,0.0003059626,0.0002728561,0.0001955753,0.0002769323,0.0003101438,0.0002432474,0.001897276],"category_scores_gemma":[0.0002502779,0.0001590517,0.0002291188,0.0002022897,0.0001362952,0.0001898968,0.0002235244,0.0004073715,0.0006313358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003973625,"about_ca_system_score_gemma":0.0003518253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003946433,"about_ca_topic_score_gemma":0.0005758423,"domain_scores_codex":[0.9997639,0.00006761488,0.00002316939,0.00003336474,0.00005758136,0.00005446954],"domain_scores_gemma":[0.9999042,0.00001192786,0.00001743611,0.000008772296,0.00002519702,0.00003253291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000237621,0.0001557676,0.0001489055,0.0002820993,0.00001406759,0.0001422167,0.00004410149,0.00123887,0.9826089,0.0006050344,0.0002055732,0.01431674],"study_design_scores_gemma":[0.0001540529,0.003655506,0.0008022182,0.00002498069,0.00003868432,0.0004505408,0.00003081884,0.001215794,0.9763387,0.0001053702,0.01716506,0.00001813788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9677573,0.009390386,0.01298804,0.0002673409,0.00007249403,0.00061754,0.0009608348,0.0001092036,0.007836808],"genre_scores_gemma":[0.9561066,0.008466176,0.0259714,0.0002087952,0.00004698575,0.0004672128,0.001431354,0.00004037013,0.007261116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001897276,"threshold_uncertainty_score":0.006347001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03079727548125914,"score_gpt":0.270274954460844,"score_spread":0.2394776789795849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}