{"id":"W2532584709","doi":"10.1534/genetics.116.194134","title":"Chromatin Association of Gcn4 Is Limited by Post-translational Modifications Triggered by its DNA-Binding in <i>Saccharomyces cerevisiae</i>","year":2016,"lang":"en","type":"article","venue":"Genetics","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Saccharomyces cerevisiae; Chromatin; Biology; Genetics; DNA; Posttranslational modification; DNA-binding protein; Association (psychology); Cell biology; Transcription factor; Yeast; Gene; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002093646,0.0001393985,0.0001614739,0.00005287522,0.00004821828,0.00001529064,0.0001794531,0.0002207298,0.0001089194],"category_scores_gemma":[0.0001157583,0.0001249945,0.00007228742,0.0001347797,0.00002645596,0.000006600815,0.0000319253,0.00005362873,0.00002538996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002767579,"about_ca_system_score_gemma":0.0000764413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004151386,"about_ca_topic_score_gemma":0.00001484097,"domain_scores_codex":[0.9988335,0.00008565767,0.0003716264,0.0002735794,0.0002071958,0.0002283993],"domain_scores_gemma":[0.9992869,0.0000509082,0.0002325692,0.0002103038,0.0001596069,0.00005970896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001932693,0.0000667718,0.003439281,0.00002191011,0.00003495451,1.041547e-7,0.0001074803,0.000002381358,0.983741,0.00001966382,0.01036431,0.002182798],"study_design_scores_gemma":[0.0008348072,0.0001026231,0.001423014,0.00003521369,0.00001760874,0.000001133244,0.00002684033,0.00004272575,0.975862,0.00004391955,0.02144241,0.0001676919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934508,0.001907007,0.0004260522,0.001678287,0.00004702386,0.0002866346,0.001832709,0.00001085492,0.0003606542],"genre_scores_gemma":[0.9965529,0.0009322478,0.0006610345,0.0001604965,0.000060462,0.00003541642,0.0004985076,0.00002123805,0.001077638],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0110781,"threshold_uncertainty_score":0.5097126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01250139615916505,"score_gpt":0.2374675589486402,"score_spread":0.2249661627894751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}