{"id":"W2533157543","doi":"10.1182/blood.v114.22.132.132","title":"Lenalidomide, Bortezomib, Pegylated Liposomal Doxorubicin, and Dexamethasone in Newly Diagnosed Multiple Myeloma: Updated Results of Phase I/II MMRC Trial.","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Lenalidomide; Medicine; Multiple myeloma; Dexamethasone; Regimen; Bortezomib; Internal medicine; Thalidomide; Melphalan; Transplantation; Phases of clinical research; Gastroenterology; Oncology; Urology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003478806,0.0008146406,0.002217092,0.0004155407,0.0002419012,0.0009309824,0.0008283636,0.0008157347,0.001761455],"category_scores_gemma":[0.001425736,0.0004402041,0.001035017,0.0006758232,0.0002751755,0.0007725331,0.0003660669,0.001690726,0.000461372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009202036,"about_ca_system_score_gemma":0.000956016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001380418,"about_ca_topic_score_gemma":0.004539578,"domain_scores_codex":[0.9990447,0.000589481,0.00006880931,0.0000903907,0.0001013522,0.0001051646],"domain_scores_gemma":[0.9988373,0.0002092045,0.0004502483,0.00008303583,0.00007078994,0.0003494589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7011871,0.01097839,0.05656232,0.002321028,0.005399018,0.0005319162,0.0002742084,0.002986746,0.01874065,0.0002037915,0.01491317,0.1859016],"study_design_scores_gemma":[0.7002791,0.1111309,0.1594103,0.0003274474,0.005691985,0.001591872,0.00009763516,0.001934398,0.003168697,0.000244078,0.01605303,0.00007049399],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9478047,0.03547829,0.0006778762,0.001693669,0.0002523365,0.00276518,0.006004708,0.0001992969,0.005123924],"genre_scores_gemma":[0.9672487,0.01019611,0.002016024,0.002100189,0.0005088933,0.001897632,0.0135832,0.00005008696,0.002399109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003478806,"threshold_uncertainty_score":0.01839793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02599818394216666,"score_gpt":0.3137119133069846,"score_spread":0.287713729364818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}