{"id":"W2533329878","doi":"10.1016/j.mce.2016.10.022","title":"LUMAN/CREB3 is a key regulator of glucocorticoid-mediated stress responses","year":2016,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Regulator; Unfolded protein response; Glucocorticoid; Endoplasmic reticulum; Glucocorticoid receptor; Corticosterone; Internal medicine; Endocrinology; Biology; Receptor; Transcription factor; Cell biology; Gene; Hormone; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002419588,0.0002312129,0.0003516151,0.0001935342,0.00006689994,0.00001880714,0.000292322,0.0001082333,0.0003081117],"category_scores_gemma":[0.0004760153,0.0001733912,0.0001312664,0.0001911401,0.0003918179,0.00006606858,0.0002084221,0.0001071861,0.00007972716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000182608,"about_ca_system_score_gemma":0.00006532602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004156401,"about_ca_topic_score_gemma":0.000003753554,"domain_scores_codex":[0.9978656,0.000310577,0.0003768332,0.0006207195,0.0002777525,0.0005485156],"domain_scores_gemma":[0.9986892,0.0003776769,0.0001632364,0.000593933,0.00005050281,0.0001254758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004708398,0.00006911126,0.003471847,0.00002944188,0.00002114632,0.0006160263,0.00008458282,9.152321e-7,0.9833347,0.004511417,0.00005074188,0.00733925],"study_design_scores_gemma":[0.001201481,0.0003294217,0.002410576,0.00004116642,0.0000278507,0.0001099129,0.00004374465,0.00003933352,0.9890489,0.0003660647,0.006165028,0.000216526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952852,0.001372756,0.001408935,0.0008204599,0.0001519886,0.0002594327,0.0001055176,0.00006104784,0.0005346273],"genre_scores_gemma":[0.9964631,0.0007668211,0.00004773265,0.000533325,0.00001771416,0.00002857241,0.000002487218,0.00003197518,0.002108318],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007122724,"threshold_uncertainty_score":0.7070689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01544451774793621,"score_gpt":0.2448861830206914,"score_spread":0.2294416652727552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}