{"id":"W2533595896","doi":"10.1097/tp.0000000000001541","title":"Is There a Role for mTOR Inhibitors in Renal Transplantation?","year":2016,"lang":"en","type":"letter","venue":"Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Discovery and development of mTOR inhibitors; Tolerability; Medicine; Transplantation; PI3K/AKT/mTOR pathway; Kidney transplantation; Intensive care medicine; Oncology; Internal medicine; Adverse effect; Biology; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003496327,0.0006330518,0.001724296,0.0008711988,0.002047755,0.002802527,0.001511469,0.02121467,0.00486715],"category_scores_gemma":[0.02385685,0.000466407,0.001088344,0.0009455051,0.002075318,0.004434856,0.001408246,0.03294411,0.005484113],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002832331,"about_ca_system_score_gemma":0.002792829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00204269,"about_ca_topic_score_gemma":0.004388055,"domain_scores_codex":[0.9974236,0.000849211,0.000507823,0.0003107061,0.0006885675,0.0002201191],"domain_scores_gemma":[0.9901937,0.005851431,0.0008387414,0.0002279708,0.001731986,0.001156135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007617142,0.00004432962,0.0008320942,0.00015131,0.00002293824,0.001105168,0.00007994376,0.00007388401,0.000114579,0.001734351,0.9658679,0.02989732],"study_design_scores_gemma":[0.0002066115,0.0001434824,0.00157085,0.00103501,0.00005445972,0.005315308,0.0003195435,0.0003628829,0.0002803032,0.01172048,0.9789131,0.00007798547],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0001802988,0.004628995,0.00007700507,0.9774206,0.01693885,0.000004034573,0.00002842877,0.00001796014,0.0007038199],"genre_scores_gemma":[0.002019823,0.007795589,0.0001966691,0.8997073,0.08817115,0.00001803125,0.00003199865,0.00001594156,0.002043501],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02121467,"threshold_uncertainty_score":0.02055013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02095190144172816,"score_gpt":0.2913753936269654,"score_spread":0.2704234921852373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}