{"id":"W2534096574","doi":"10.1080/15384101.2016.1241917","title":"p53 oligomerization status modulates cell fate decisions between growth, arrest and apoptosis","year":2016,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Cell fate determination; Biology; Programmed cell death; Cell growth; Cell cycle checkpoint; Apoptosis; Cell biology; Cell; Cell cycle; Mutation; Gene; Transcription factor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007911018,0.0001801662,0.000257845,0.0001390515,0.00009738715,0.0000229198,0.00007374265,0.0001427174,0.00008975424],"category_scores_gemma":[0.0001094485,0.0001380402,0.00007141486,0.0002310887,0.00008644157,0.00009831461,0.00007374107,0.0001209117,0.0001869271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009053779,"about_ca_system_score_gemma":0.00006645481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008136171,"about_ca_topic_score_gemma":0.000004507222,"domain_scores_codex":[0.9987281,0.0000349252,0.0002571338,0.000372378,0.0002288837,0.0003785847],"domain_scores_gemma":[0.9989988,0.0001460925,0.00009041584,0.0003484845,0.00008795759,0.00032822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004693339,0.00008287982,0.0182597,0.00004769616,0.00003201705,0.000009002434,0.0002439746,0.00002637359,0.9652256,0.00003111242,0.0004940529,0.0155006],"study_design_scores_gemma":[0.002742721,0.00019463,0.03204638,0.0001794382,0.0001796378,0.000003369602,0.00004063176,0.0001352205,0.9590428,0.0006877125,0.004482536,0.0002648871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856874,0.0005449991,0.007972078,0.0003867676,0.0002117069,0.000309785,0.00005933912,0.0001046022,0.004723278],"genre_scores_gemma":[0.996857,0.001243346,0.0009709295,0.00009486947,0.0001371371,0.0000157011,0.00005443493,0.00005553145,0.0005709956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01523571,"threshold_uncertainty_score":0.5629115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.011839893974512,"score_gpt":0.2311692990688475,"score_spread":0.2193294050943355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}