{"id":"W2534202907","doi":"10.1038/srep35640","title":"Recombinant Reg3β protein protects against streptozotocin-induced β-cell damage and diabetes","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Priority Academic Program Development of Jiangsu Higher Education Institutions; Government of Jiangsu Province; McGill University Health Centre; National Natural Science Foundation of China; McGill University","keywords":"Islet; Streptozotocin; Diabetes mellitus; Recombinant DNA; Cell; Apoptosis; Regeneration (biology); Downregulation and upregulation; Insulin; Endocrinology; Internal medicine; Cell biology; Biology; Medicine; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000224988,0.0006884541,0.0003675997,0.0003880497,0.0001133166,0.0002418154,0.0001922317,0.0002231411,0.00118115],"category_scores_gemma":[0.0001271365,0.0001792656,0.0003904616,0.0002424644,0.000215255,0.0001671224,0.000162206,0.0008081187,0.0005277988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001520996,"about_ca_system_score_gemma":0.000277623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003176689,"about_ca_topic_score_gemma":0.000280285,"domain_scores_codex":[0.9998949,0.00001492967,0.0000112613,0.0000180947,0.00002826811,0.0000326867],"domain_scores_gemma":[0.9998017,0.00001635896,0.00007279818,0.00002807316,0.00001721784,0.00006390332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005347414,0.0001023613,0.0001739313,0.00004165795,0.00001002645,0.00003973373,0.00001070369,0.00003636824,0.9976876,0.00004342045,0.00003820529,0.00128125],"study_design_scores_gemma":[0.0001161744,0.001700786,0.004867133,0.00001423825,0.00005095266,0.0004261166,0.00003414483,0.0003913789,0.9897546,0.00007877972,0.002559772,0.000005741491],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944525,0.002053622,0.001644218,0.0001207179,0.00004728166,0.00002691745,0.000464619,0.0002384498,0.0009516277],"genre_scores_gemma":[0.9896147,0.002232509,0.002966175,0.0001334398,0.00003257146,0.00004006378,0.0022828,0.00009321533,0.00260451],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00118115,"threshold_uncertainty_score":0.003951371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01333839663326093,"score_gpt":0.2257811671248478,"score_spread":0.2124427704915868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}