{"id":"W2535141078","doi":"10.1101/gr.209841.116","title":"Direct chromosome-length haplotyping by single-cell sequencing","year":2016,"lang":"en","type":"article","venue":"Genome Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"European Research Council","keywords":"Biology; International HapMap Project; Genetics; Haplotype; Ploidy; Genome; Loss of heterozygosity; Indel; Chromosome; Computational biology; Single-nucleotide polymorphism; Allele; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005094871,0.0003183629,0.0004109138,0.0004582389,0.0002370908,0.0005510266,0.0003950589,0.000454167,0.001930114],"category_scores_gemma":[0.0008230268,0.0002879853,0.0003225663,0.0003711372,0.0003103891,0.0002931332,0.0005942423,0.0005321565,0.001098851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000212985,"about_ca_system_score_gemma":0.0003061972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008652898,"about_ca_topic_score_gemma":0.003529192,"domain_scores_codex":[0.9997194,0.00005016273,0.00002091129,0.0001145691,0.00007526813,0.0000196347],"domain_scores_gemma":[0.9992913,0.000302633,0.00008651047,0.0001915413,0.00008106139,0.00004701425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006310116,0.00001126714,0.003337827,0.0001204202,0.00004134914,0.00007007513,0.000065364,0.001463156,0.9732229,0.0009043666,0.0002908539,0.02040947],"study_design_scores_gemma":[0.00003767615,0.0001901859,0.02898282,0.00004123764,0.00007892233,0.0007626299,0.0001343607,0.03616278,0.9040677,0.005000808,0.02448286,0.00005803589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3507575,0.001925657,0.6290914,0.0001719073,0.0001111438,0.0003436825,0.01043361,0.002156307,0.005008779],"genre_scores_gemma":[0.4839981,0.001530336,0.5016593,0.0002250418,0.00003060656,0.00041068,0.007932024,0.0005912492,0.003622666],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001930114,"threshold_uncertainty_score":0.006456912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04643468842197938,"score_gpt":0.2971124715114068,"score_spread":0.2506777830894274,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}