{"id":"W2535539542","doi":"10.1007/s40263-016-0385-9","title":"Pharmacogenetics and Imaging–Pharmacogenetics of Antidepressant Response: Towards Translational Strategies","year":2016,"lang":"en","type":"review","venue":"CNS Drugs","topic":"Treatment of Major Depression","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Pharmacogenetics; Antidepressant; Neuroimaging; Medicine; Pharmacology; Psychology; Psychiatry; Biology; Genetics; Gene; Anxiety","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001369961,0.0008537426,0.002214424,0.001480662,0.0001449009,0.001284811,0.001091786,0.001339372,0.002530419],"category_scores_gemma":[0.00181563,0.0003009668,0.0008589039,0.001456852,0.0004915299,0.001161861,0.0006900254,0.001910307,0.0008090209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006870637,"about_ca_system_score_gemma":0.00138338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001442994,"about_ca_topic_score_gemma":0.003513708,"domain_scores_codex":[0.9997131,0.00008220325,0.00005328243,0.00005383494,0.0000765816,0.00002095304],"domain_scores_gemma":[0.9990124,0.0006101623,0.0001461615,0.00002358799,0.0001726892,0.0000350361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001871511,0.0001040418,0.00062643,0.01897939,0.0004067794,0.0001772666,0.00003483879,0.0004459612,0.001536872,0.003674476,0.0154933,0.9583334],"study_design_scores_gemma":[0.0002056113,0.0003636391,0.004660395,0.01974836,0.001900568,0.002419088,0.0001285399,0.0007700736,0.001202362,0.009073502,0.9594527,0.00007517425],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008799361,0.9989315,0.0001622835,0.0003866774,0.0000869371,0.000003884737,0.00001382131,0.000003675863,0.0003231797],"genre_scores_gemma":[0.001054788,0.9976173,0.0004482642,0.0004223361,0.0002340128,0.000006867958,0.00002756786,0.000001155887,0.0001876167],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002530419,"threshold_uncertainty_score":0.008465111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03917798352743512,"score_gpt":0.3908195862422717,"score_spread":0.3516416027148366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}