{"id":"W2536040170","doi":"10.1089/hum.2016.090","title":"FMRP Expression Levels in Mouse Central Nervous System Neurons Determine Behavioral Phenotype","year":2016,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Central nervous system; Phenotype; Neuroscience; Biology; Expression (computer science); Nervous system; Genetics; Gene; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005642838,0.0002040642,0.0001443897,0.00005183916,0.00008710568,0.00001894155,0.0002366952,0.00009884721,0.00005033961],"category_scores_gemma":[0.000002617758,0.0001556256,0.00006758535,0.00004506988,0.00005092454,0.000004257753,0.00008452078,0.00005050602,0.00001197829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002590999,"about_ca_system_score_gemma":0.00003488364,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001602784,"about_ca_topic_score_gemma":0.00005839295,"domain_scores_codex":[0.9987924,0.00007161577,0.0002329761,0.0004014427,0.0001224942,0.0003790828],"domain_scores_gemma":[0.9994594,0.000003459947,0.00006252264,0.0003553897,0.00002486357,0.00009439592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006905103,0.0001154391,0.00248126,0.000005007262,0.000006012272,0.00001189882,0.00007618755,0.0000113157,0.9901124,0.000009578534,0.0001466349,0.006955173],"study_design_scores_gemma":[0.00139651,0.0003693203,0.1253277,0.00001633442,0.00000241927,0.000008804343,0.00002702131,0.000002757665,0.8712814,0.00001589973,0.001325578,0.000226306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989244,0.0002988345,0.0001511103,0.00003152803,0.0001370985,0.0002329773,0.00003010675,0.00002451064,0.0001694878],"genre_scores_gemma":[0.9983287,0.0001910088,0.0001923199,0.0001243643,0.00005403932,0.00003177557,0.00003441217,0.00004862474,0.0009947529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1228464,"threshold_uncertainty_score":0.6346228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03387962706968224,"score_gpt":0.2678009686481405,"score_spread":0.2339213415784583,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}