{"id":"W2536040170","doi":"10.1089/hum.2016.090","title":"FMRP Expression Levels in Mouse Central Nervous System Neurons Determine Behavioral Phenotype","year":2016,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Central nervous system; Phenotype; Neuroscience; Biology; Expression (computer science); Nervous system; Genetics; Gene; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002456935,0.0005881388,0.0003758278,0.0007460916,0.0002628982,0.0004988608,0.0003222991,0.0007905109,0.001796873],"category_scores_gemma":[0.0001445056,0.0003422992,0.0004575191,0.0002917231,0.000502788,0.0003605871,0.0002805673,0.001594569,0.0009152675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004579461,"about_ca_system_score_gemma":0.0001918481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008699194,"about_ca_topic_score_gemma":0.001523625,"domain_scores_codex":[0.9995567,0.00003530699,0.00005970458,0.0001535738,0.00009784889,0.00009688745],"domain_scores_gemma":[0.9997039,0.00003971991,0.0001047866,0.00003347496,0.00003201681,0.00008602121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006095625,0.00002147121,0.00009776025,0.0000178003,0.000003761282,0.00002209096,0.00001627798,0.00001642386,0.9993715,0.00002620211,0.00001214878,0.0003335408],"study_design_scores_gemma":[0.00001391205,0.000301318,0.005675176,0.00001150379,0.00003350401,0.0002128306,0.00004333799,0.0002713053,0.9926999,0.00004475946,0.0006857837,0.000006711707],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988383,0.00193611,0.005496281,0.0001195778,0.00004098286,0.00005416387,0.001942976,0.000217619,0.001809346],"genre_scores_gemma":[0.981452,0.001966676,0.006921972,0.000106541,0.00001679955,0.0002258643,0.00234513,0.0001487547,0.006816249],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001796873,"threshold_uncertainty_score":0.006011128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03387962706968224,"score_gpt":0.2678009686481405,"score_spread":0.2339213415784583,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}