{"id":"W2536093755","doi":"10.1182/blood.v120.21.2370.2370","title":"Deep Phenotypic Characterization of Primitive Stem and Progenitor Compartments Reveals the Cellular Architecture of Aplastic Anemia.","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Aplastic anemia; Progenitor cell; Stem cell; Biology; Myeloid; Haematopoiesis; CD38; CD34; Immunology; Myelodysplastic syndromes; Progenitor; Cancer research; Bone marrow; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012957,0.0001823682,0.0001563379,0.0004318175,0.0001367594,0.0002479233,0.000115759,0.000192692,0.001056791],"category_scores_gemma":[0.0001292827,0.00009357004,0.00008881908,0.0001931791,0.0001456473,0.0001693245,0.0003024588,0.0003313627,0.0002804002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001248359,"about_ca_system_score_gemma":0.00007520294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003136254,"about_ca_topic_score_gemma":0.0004793948,"domain_scores_codex":[0.9999328,0.000009782313,0.00000632835,0.00001420388,0.00002096028,0.00001590155],"domain_scores_gemma":[0.9999361,0.00001212565,0.00001124324,0.000009086682,0.00001332375,0.00001807002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000834667,0.00001279471,0.002362818,0.00001766066,0.000003401843,0.00005108581,0.0000479726,0.0001023346,0.9897995,0.0001604811,0.00003232464,0.00732621],"study_design_scores_gemma":[0.00003589129,0.0008338526,0.1613227,0.00002864121,0.00006372081,0.004066622,0.0002894284,0.01638715,0.8087287,0.001104708,0.007118533,0.00002002519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878925,0.0008206048,0.009640384,0.00004682999,0.000003992761,0.00003259845,0.0002912926,0.00008556241,0.001186262],"genre_scores_gemma":[0.9897036,0.0002997471,0.008401334,0.00004910651,0.000004578022,0.00003116308,0.0005293675,0.00001807348,0.00096291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001056791,"threshold_uncertainty_score":0.00353533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01019793893154431,"score_gpt":0.1987873919322388,"score_spread":0.1885894530006945,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}