{"id":"W2536831387","doi":"10.1182/blood.v120.21.4433.4433","title":"Associations Between Baseline Mutation Status and Response to Treatment with Omacetaxine Mepesuccinate in Heavily Pretreated Patients with Chronic Myeloid Leukemia","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Internal medicine; Myeloid leukemia; Tolerability; Imatinib; Phases of clinical research; Gastroenterology; Oncology; Immunology; Adverse effect; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003227265,0.0001826802,0.0003478011,0.0003468913,0.0001820669,0.0002641729,0.0001626565,0.0005009775,0.001980929],"category_scores_gemma":[0.0009904588,0.0001134324,0.0002897556,0.0004000709,0.0001571014,0.0002334867,0.0001344049,0.0003955307,0.0001901789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001863231,"about_ca_system_score_gemma":0.0001493538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009101463,"about_ca_topic_score_gemma":0.001029686,"domain_scores_codex":[0.9998221,0.0000517984,0.00002081658,0.00003996456,0.00002863107,0.00003677907],"domain_scores_gemma":[0.9990668,0.0002631156,0.0003419299,0.00004059479,0.00005439,0.0002331353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004655222,0.000139394,0.9893499,0.0000135088,0.00007534152,0.0001139735,0.00002175872,0.0001367822,0.002904764,0.00001658782,0.0001445455,0.002428218],"study_design_scores_gemma":[0.0001233506,0.001061782,0.9977177,0.000004425426,0.00003468355,0.000218111,0.00003060654,0.0003416174,0.0002343274,0.00001418346,0.0002155064,0.000003733038],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993804,0.0001881059,0.00001896869,0.00002303744,0.000002780756,0.000007312761,0.0001674972,0.000001798889,0.0002101639],"genre_scores_gemma":[0.9996463,0.00003757951,0.00001950012,0.00001773315,0.000006303814,0.000007687108,0.0001934834,7.416478e-7,0.00007062034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001980929,"threshold_uncertainty_score":0.006626844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01070676731487724,"score_gpt":0.2531531663544169,"score_spread":0.2424463990395396,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}