{"id":"W2537989070","doi":"10.1016/j.celrep.2016.09.064","title":"Androgen Receptor Tumor Suppressor Function Is Mediated by Recruitment of Retinoblastoma Protein","year":2016,"lang":"en","type":"article","venue":"Cell Reports","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"National Cancer Institute; National Institutes of Health; U.S. Department of Defense","keywords":"Androgen receptor; Repressor; Retinoblastoma protein; Psychological repression; Biology; Cancer research; Prostate cancer; Hyperphosphorylation; Gene; Retinoblastoma; Activator (genetics); Transcription factor; Transcription (linguistics); Cyclin-dependent kinase; Cell growth; Androgen; Cell cycle; Cell biology; Kinase; Gene expression; Endocrinology; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002509111,0.0001455404,0.0002708196,0.00007450501,0.00003919772,0.000006223217,0.00003950726,0.00008026358,0.001741415],"category_scores_gemma":[0.00009764792,0.00008456535,0.00008892345,0.0001398499,0.00009725869,0.00006186402,0.0000374429,0.00007763314,0.00007450749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001427388,"about_ca_system_score_gemma":0.0001882994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002055838,"about_ca_topic_score_gemma":8.491218e-7,"domain_scores_codex":[0.9984533,0.00004154349,0.0004118087,0.0003643878,0.0004478187,0.0002810934],"domain_scores_gemma":[0.9989097,0.00003678049,0.0002593849,0.0004116382,0.0001855721,0.000196927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008031768,0.0002479892,0.007734063,0.0001318299,0.00007108429,0.0002781586,0.0000834638,1.257718e-8,0.9420026,0.000001017575,0.04515402,0.003492571],"study_design_scores_gemma":[0.001391569,0.0008797465,0.0006528166,0.0002188043,0.00004757361,0.00005178399,0.00002570063,9.462553e-7,0.8815581,0.0000431735,0.1150416,0.00008827519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919408,0.000864298,0.00002385017,0.001137071,0.0001759925,0.001905043,0.00005440544,0.00005909105,0.003839456],"genre_scores_gemma":[0.9607757,0.0001224145,0.00009583752,0.00007499853,0.00006797084,0.0003734407,0.0001089978,0.00003073248,0.03834992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06988755,"threshold_uncertainty_score":0.9991711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02759952317313718,"score_gpt":0.2798678567292726,"score_spread":0.2522683335561354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}