{"id":"W2538873836","doi":"10.3390/ncrna2040012","title":"TWEAK Negatively Regulates Human Dicer","year":2016,"lang":"en","type":"article","venue":"Non-Coding RNA","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University; Université Laval; Centre hospitalier de l'Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Dicer; microRNA; Cell biology; Gene silencing; Biology; Small interfering RNA; Ribonuclease III; RNA interference; RNA-binding protein; Molecular biology; HEK 293 cells; Transfection; RNA; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003106105,0.0004154045,0.0003811188,0.000306324,0.0003637555,0.0006975018,0.0002979125,0.0003999134,0.003060764],"category_scores_gemma":[0.0005218511,0.0002333033,0.0002768135,0.000128558,0.0003022884,0.0003101081,0.0004507276,0.0005244908,0.00162857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005794386,"about_ca_system_score_gemma":0.0002857306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003953023,"about_ca_topic_score_gemma":0.000471721,"domain_scores_codex":[0.9994435,0.0001025657,0.00005896799,0.0001523285,0.000152167,0.00009054069],"domain_scores_gemma":[0.9994969,0.0001133085,0.0001732503,0.00005503713,0.00009111471,0.00007030273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007274289,0.000006461405,0.0001270245,0.00003077488,0.000003323269,0.00009204179,0.000009596281,0.0000373882,0.9984748,0.0001186666,0.00009058648,0.0009365906],"study_design_scores_gemma":[0.00001495585,0.00006979452,0.001802619,0.000005715549,0.000007688634,0.0006039415,0.00001573179,0.0007673548,0.9903376,0.0000767551,0.006290473,0.000007449941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.962128,0.01109421,0.01763256,0.0005838776,0.0002888144,0.00009922885,0.001087479,0.0004846982,0.006601288],"genre_scores_gemma":[0.9870603,0.001045369,0.003723295,0.0002200582,0.0000252713,0.00003503063,0.001063273,0.00007948636,0.00674779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003060764,"threshold_uncertainty_score":0.01023924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01239332486795107,"score_gpt":0.2601197361810638,"score_spread":0.2477264113131127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}