{"id":"W2538873836","doi":"10.3390/ncrna2040012","title":"TWEAK Negatively Regulates Human Dicer","year":2016,"lang":"en","type":"article","venue":"Non-Coding RNA","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University; Université Laval; Centre hospitalier de l'Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Dicer; microRNA; Cell biology; Gene silencing; Biology; Small interfering RNA; Ribonuclease III; RNA interference; RNA-binding protein; Molecular biology; HEK 293 cells; Transfection; RNA; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001145286,0.0001355756,0.0001038758,0.00004041601,0.0001090621,0.00002238895,0.000160268,0.0001149945,0.0001286729],"category_scores_gemma":[0.0000620069,0.0001022168,0.00008212153,0.0000552992,0.00008726605,0.000007070145,0.00008895056,0.00003477678,0.00006000711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003080409,"about_ca_system_score_gemma":0.00003138331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001066811,"about_ca_topic_score_gemma":0.000008281894,"domain_scores_codex":[0.9991684,0.0000287567,0.0001625209,0.0003101963,0.0001110245,0.000219119],"domain_scores_gemma":[0.9994233,0.00001299277,0.00009086693,0.0003231922,0.00006806772,0.00008156319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002025697,0.00001900435,0.001356518,0.000009773512,0.00003125706,0.000001495064,0.00002117155,0.00000220117,0.9903361,0.000254649,0.004650679,0.003296869],"study_design_scores_gemma":[0.000533672,0.00005685675,0.0365203,0.00006265426,0.00001485519,0.000003512418,0.00000788026,0.000009988605,0.9528615,0.0005319251,0.009214134,0.000182698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909838,0.0001352899,0.002859451,0.0002488756,0.000114329,0.0001285444,0.00001374768,0.00002594373,0.005490052],"genre_scores_gemma":[0.9958515,0.00002589325,0.0003701067,0.00008500189,0.0003800976,0.00001306259,0.000030691,0.00002789543,0.003215744],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0374746,"threshold_uncertainty_score":0.4168279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01239332486795107,"score_gpt":0.2601197361810638,"score_spread":0.2477264113131127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}