{"id":"W2539127255","doi":"10.1182/blood.v120.21.2224.2224","title":"Recombinant B-Domain Deleted Porcine Factor VIII (OBI-1) Safety and Efficacy in the Treatment of Acquired Hemophilia A: Interim Results.","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Medicine; Interim analysis; Antibody; Adverse effect; Autoantibody; Clinical trial; Internal medicine; Recombinant DNA; Bleed; Gastroenterology; Surgery; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00299998,0.000688217,0.0009744304,0.0003137708,0.0002382964,0.0007303015,0.0005052492,0.001042334,0.003687637],"category_scores_gemma":[0.001112949,0.0002315762,0.001261443,0.0002206634,0.0004470891,0.0003957445,0.0002194458,0.00138616,0.0006660999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003696301,"about_ca_system_score_gemma":0.0007044123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004361803,"about_ca_topic_score_gemma":0.000659406,"domain_scores_codex":[0.9993744,0.0003466633,0.0000423106,0.00005159559,0.00007939429,0.0001056415],"domain_scores_gemma":[0.9990304,0.0003144761,0.0002251594,0.00007048911,0.00008375134,0.000275754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6703189,0.03120786,0.00886801,0.001783672,0.002364939,0.0006299102,0.0002652939,0.002545133,0.04009407,0.0007011679,0.01396875,0.2272523],"study_design_scores_gemma":[0.3103694,0.6374757,0.02620973,0.0002093681,0.001267535,0.0007563016,0.00004606059,0.001021096,0.01125818,0.0002984568,0.01104836,0.00003980009],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9671593,0.01625307,0.001543619,0.001038206,0.0003055019,0.002689754,0.004376693,0.0001988339,0.006434883],"genre_scores_gemma":[0.9791896,0.005242001,0.002285029,0.0009881648,0.0003565425,0.001506397,0.005659642,0.00003284726,0.004739725],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003687637,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04130926597859071,"score_gpt":0.3156874200950628,"score_spread":0.2743781541164721,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}