{"id":"W2539415090","doi":"10.1021/acs.jafc.6b03755","title":"Fructosazine, a Polyhydroxyalkylpyrazine with Antimicrobial Activity: Mechanism of Inhibition against Extremely Heat Resistant <i>Escherichia coli</i>","year":2016,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Antimicrobial agents and applications","field":"Chemistry","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Alberta Innovates Bio Solutions; Natural Sciences and Engineering Research Council of Canada; Alberta Livestock and Meat Agency","keywords":"Escherichia coli; Propidium iodide; Antimicrobial; Biochemistry; Acetic acid; Chemistry; Bacteria; Mechanism of action; Microbiology; Biology; Programmed cell death; In vitro; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001375477,0.0003126918,0.0002315941,0.0001129244,0.0000862023,0.0001834154,0.0002319121,0.0004237815,0.0003644711],"category_scores_gemma":[0.0001071621,0.0001001834,0.0002249273,0.00009406944,0.0001982946,0.0002218375,0.0001412239,0.0002300588,0.000114981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000250671,"about_ca_system_score_gemma":0.0001546434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000827121,"about_ca_topic_score_gemma":0.0009002794,"domain_scores_codex":[0.9999154,0.0000195159,0.000006002976,0.00001623576,0.0000198871,0.00002299149],"domain_scores_gemma":[0.9999474,0.000008961601,0.0000214887,0.000003906202,0.00000778991,0.00001055232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001136254,0.00001456718,0.0001701283,0.00009340089,0.00000550839,0.00004098732,0.000007353831,0.00008050016,0.9969059,0.00004982976,0.00001562998,0.002502637],"study_design_scores_gemma":[0.00001215449,0.0008259672,0.002447035,0.00000561396,0.00001467801,0.0002183333,0.000008225533,0.0004233651,0.9946867,0.00001113881,0.001341924,0.000004760201],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984035,0.009182555,0.005195043,0.0001225761,0.00001915936,0.00007377759,0.000150565,0.00004851617,0.001172782],"genre_scores_gemma":[0.9919025,0.002863115,0.00365131,0.0000528723,0.000005617313,0.00002168108,0.0001216206,0.000004841544,0.001376352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000827121,"threshold_uncertainty_score":0.001818717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007091101267258849,"score_gpt":0.181147147962349,"score_spread":0.1740560466950901,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}