{"id":"W2539415090","doi":"10.1021/acs.jafc.6b03755","title":"Fructosazine, a Polyhydroxyalkylpyrazine with Antimicrobial Activity: Mechanism of Inhibition against Extremely Heat Resistant <i>Escherichia coli</i>","year":2016,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Antimicrobial agents and applications","field":"Chemistry","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Alberta Innovates Bio Solutions; Natural Sciences and Engineering Research Council of Canada; Alberta Livestock and Meat Agency","keywords":"Escherichia coli; Propidium iodide; Antimicrobial; Biochemistry; Acetic acid; Chemistry; Bacteria; Mechanism of action; Microbiology; Biology; Programmed cell death; In vitro; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005754666,0.0002388603,0.0003745046,0.00001919586,0.0001040224,0.00003215208,0.0001368042,0.0001413842,0.00007733166],"category_scores_gemma":[0.00001129559,0.0001189268,0.0001382809,0.0001386089,0.0001229923,0.0001801156,0.00005554057,0.0001994183,0.000001066399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004887159,"about_ca_system_score_gemma":0.00005249198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006262084,"about_ca_topic_score_gemma":0.000003687857,"domain_scores_codex":[0.9988979,0.00000766368,0.0004360273,0.000210652,0.0002277966,0.0002199278],"domain_scores_gemma":[0.998982,0.00002811186,0.0004816908,0.0001335389,0.0002228114,0.0001519064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001951105,0.0001874117,0.00004620343,0.0001747403,0.0001210529,0.000007355475,0.00003979174,0.000002762749,0.9981732,0.00005195653,0.0006223515,0.0003780234],"study_design_scores_gemma":[0.001414988,0.000128182,0.0008232624,0.0006280381,0.00009174432,0.000251356,0.00008797373,0.000001263621,0.995719,0.00003844928,0.0005908901,0.0002248226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964473,0.0001007311,0.0001230695,0.001157327,0.00002094237,0.00005177703,0.0001459384,0.00001836839,0.001934542],"genre_scores_gemma":[0.9985049,0.0002759066,0.0003519671,0.00005497095,0.0002527669,0.000002826738,0.00001253976,0.00001497575,0.0005291594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00245421,"threshold_uncertainty_score":0.4849693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007091101267258849,"score_gpt":0.181147147962349,"score_spread":0.1740560466950901,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}