{"id":"W2540188128","doi":"10.18632/oncotarget.12941","title":"Increased phosphorylation of eIF2α in chronic myeloid leukemia cells stimulates secretion of matrix modifying enzymes","year":2016,"lang":"en","type":"article","venue":"Oncotarget","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Cancer Institute; National Institutes of Health","keywords":"Myeloid leukemia; Secretion; Phosphorylation; Medicine; Enzyme; Cancer research; Leukemia; Internal medicine; Biology; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001544837,0.0002951658,0.0001691035,0.0002132502,0.0001513623,0.0003057675,0.00006993623,0.0002072419,0.001856419],"category_scores_gemma":[0.0001252136,0.0001237194,0.0002192461,0.0001915765,0.0001305986,0.0002183253,0.0001699419,0.0003520664,0.0006786052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001824607,"about_ca_system_score_gemma":0.0001284288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002182213,"about_ca_topic_score_gemma":0.0002932878,"domain_scores_codex":[0.9998928,0.00001833836,0.00001090348,0.00001508631,0.00002918249,0.00003373532],"domain_scores_gemma":[0.9999503,0.000009451959,0.00001520843,0.00000540187,0.000007289977,0.00001228693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003517726,0.00004065689,0.0008891891,0.00007601852,0.000006380037,0.0001855058,0.00003000909,0.00002575666,0.9960852,0.00006923448,0.0001741155,0.002066282],"study_design_scores_gemma":[0.0001607651,0.0007948017,0.08455821,0.0000377762,0.00003341272,0.001724417,0.0002608249,0.001324053,0.9029045,0.0001845944,0.008004707,0.00001198962],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934759,0.003459491,0.0008082225,0.0002011781,0.00006915585,0.00002213718,0.0004871975,0.00002452593,0.001452214],"genre_scores_gemma":[0.9933928,0.002013586,0.0009779895,0.00008236951,0.00003203575,0.00003869977,0.0008196806,0.000009158035,0.002633733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001856419,"threshold_uncertainty_score":0.006210327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007336917102611764,"score_gpt":0.249639596455128,"score_spread":0.2423026793525162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}