{"id":"W2540213618","doi":"10.1158/1557-3265.hemmal14-a19","title":"Abstract A19: MALT1 inhibition as an anchor for combinatorial therapy of ABC-DLBCL.","year":2015,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Université de Montréal","funders":"","keywords":"Cancer research; breakpoint cluster region; Diffuse large B-cell lymphoma; Chemistry; Cell growth; Biology; Lymphoma; Molecular biology; Cell biology; Receptor; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.006325732,0.0001458503,0.0003565725,0.00008399364,0.0002235582,0.0000316615,0.0003345246,0.000423664,0.0009536217],"category_scores_gemma":[0.0006012387,0.0001269754,0.0001632889,0.0002398926,0.0008006728,0.0001676555,0.00009137276,0.001152775,0.00007070229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001031517,"about_ca_system_score_gemma":0.000695677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001918901,"about_ca_topic_score_gemma":0.00003746347,"domain_scores_codex":[0.9971451,0.000878916,0.0005778075,0.0004314704,0.0004446901,0.0005219917],"domain_scores_gemma":[0.9968122,0.001166446,0.0001598278,0.0002474945,0.001045964,0.0005680968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.06000452,0.02149067,0.1774952,0.0003644865,0.0009022372,0.0001266347,0.001223172,0.00004548359,0.06387815,0.02561027,0.3270511,0.3218081],"study_design_scores_gemma":[0.02859462,0.006725105,0.04530979,0.00008673361,0.00003988582,0.000003995844,0.0004070419,0.0004301516,0.08396085,0.04139673,0.7926006,0.0004445624],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898733,0.00114646,0.00001164622,0.001395038,0.003561897,0.0008467446,0.0001516156,0.00003036352,0.002982871],"genre_scores_gemma":[0.9943081,0.002281427,0.00005904544,0.0006482708,0.002144471,0.0001936441,0.00004461906,0.00002746193,0.000292976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4655495,"threshold_uncertainty_score":0.9999596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.7850792158000355,"score_gpt":0.6958353942198646,"score_spread":0.08924382158017086,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}