{"id":"W2540781052","doi":"10.1074/jbc.m116.760249","title":"Nrf2 Transcription Factor Can Directly Regulate mTOR","year":2016,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"PI3K/AKT/mTOR pathway; Transcription factor; Transcription (linguistics); Biology; Cell biology; Promoter; Gene; Signal transduction; Chemistry; Gene expression; Molecular biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001562381,0.000430766,0.0003211887,0.0003000191,0.000365524,0.0003762787,0.0002121864,0.0003545002,0.005886661],"category_scores_gemma":[0.0001501095,0.000130471,0.0004946339,0.0002328289,0.0001694169,0.0003488544,0.0003146356,0.0004390229,0.002067472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003645748,"about_ca_system_score_gemma":0.0002247937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006156919,"about_ca_topic_score_gemma":0.001055166,"domain_scores_codex":[0.9998044,0.00002586437,0.00001590628,0.00006530056,0.00004896899,0.00003959402],"domain_scores_gemma":[0.9999297,0.00000862779,0.00001577815,0.00001059828,0.00002197976,0.00001346786],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002917572,0.00004977687,0.0007026995,0.0004337606,0.00003295983,0.0001943945,0.00004761634,0.0001346092,0.9864465,0.001032971,0.001519637,0.009113385],"study_design_scores_gemma":[0.00004914093,0.0002993282,0.01223984,0.00006645585,0.00007705441,0.0007690542,0.0001094329,0.001391868,0.9035454,0.0006945911,0.08072818,0.0000296109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8228109,0.07372476,0.0330369,0.002618777,0.001300102,0.0002439848,0.01254034,0.001638179,0.05208603],"genre_scores_gemma":[0.9456093,0.01050634,0.006554367,0.0006536885,0.0001698038,0.0001730108,0.007887516,0.0001437355,0.02830223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005886661,"threshold_uncertainty_score":0.0196929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02037423024992211,"score_gpt":0.2400089722672963,"score_spread":0.2196347420173742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}