{"id":"W2540781052","doi":"10.1074/jbc.m116.760249","title":"Nrf2 Transcription Factor Can Directly Regulate mTOR","year":2016,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"PI3K/AKT/mTOR pathway; Transcription factor; Transcription (linguistics); Biology; Cell biology; Promoter; Gene; Signal transduction; Chemistry; Gene expression; Molecular biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000143813,0.000193465,0.0002729908,0.00001603049,0.00004138253,0.0000145091,0.0003061544,0.0003032028,0.0001813089],"category_scores_gemma":[0.0002508565,0.0001124591,0.0002647201,0.00004004613,0.0001834329,0.000005165468,0.00004936472,0.0001367147,0.000003963794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004326274,"about_ca_system_score_gemma":0.00006095919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001269453,"about_ca_topic_score_gemma":9.850561e-7,"domain_scores_codex":[0.998883,0.00004595128,0.0004177001,0.0002629407,0.0001299688,0.0002604135],"domain_scores_gemma":[0.999092,0.0000277942,0.0003002511,0.0002069923,0.0001820712,0.0001908259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002361415,0.00006333093,0.002522412,0.00001325849,0.00006161504,0.00000646192,0.00001390802,7.060193e-7,0.9926468,0.000002685641,0.0007244612,0.003708225],"study_design_scores_gemma":[0.0007187937,0.0002237093,0.00524371,0.00003728397,0.000012748,0.00006215492,0.00002540163,4.061508e-7,0.9785399,0.0002596495,0.0146896,0.0001866668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973218,0.0006813481,0.0006218752,0.0005558114,0.0001506356,0.00005166058,0.00009456254,0.000008188233,0.0005141366],"genre_scores_gemma":[0.997151,0.000675799,0.0004294733,0.0001246316,0.000865508,0.000002796412,0.00002068303,0.00001322754,0.0007168447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01410692,"threshold_uncertainty_score":0.4585949,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02037423024992211,"score_gpt":0.2400089722672963,"score_spread":0.2196347420173742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}