{"id":"W2541175640","doi":"10.1002/pros.23269","title":"Suppression of LIM and SH3 Domain Protein 1 (LASP1) Negatively Regulated by Androgen Receptor Delays Castration Resistant Prostate Cancer Progression","year":2016,"lang":"en","type":"article","venue":"The Prostate","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Terry Fox Research Institute; Prostate Cancer Canada","keywords":"LNCaP; Prostate cancer; Cell growth; Cell cycle; Cancer research; Androgen receptor; Gene knockdown; Biology; Endocrinology; Cyclin D1; Internal medicine; Cancer; Medicine; Cell culture; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009306806,0.00026034,0.0002137318,0.0002036098,0.0001472483,0.0002259664,0.0002200866,0.0001674524,0.001551663],"category_scores_gemma":[0.00007881758,0.0001125214,0.0002102534,0.0001358183,0.0002352551,0.0001248187,0.0001358594,0.0006459358,0.0002992826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003144775,"about_ca_system_score_gemma":0.0003407615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007087418,"about_ca_topic_score_gemma":0.001512422,"domain_scores_codex":[0.9999082,0.00001020234,0.000005777073,0.00002144953,0.00002746898,0.00002699017],"domain_scores_gemma":[0.9999063,0.00001402654,0.00003033828,0.000007546518,0.000007310967,0.00003441881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001122237,0.00003615979,0.0001150477,0.00003616421,0.000003445145,0.00002695797,0.000007667072,0.00006483561,0.9986364,0.00006221019,0.00007737991,0.0008214311],"study_design_scores_gemma":[0.00002536272,0.0006251881,0.005397773,0.000004884848,0.00001622441,0.0001821821,0.00002715864,0.001508927,0.9888943,0.00003554933,0.003276762,0.000005741941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944484,0.00177696,0.001804439,0.0001135351,0.0000480069,0.00002456505,0.0004288613,0.0002151108,0.001140074],"genre_scores_gemma":[0.995229,0.0006267964,0.0009220795,0.00004561472,0.000008259707,0.00003642318,0.0004853363,0.00002370169,0.002622743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001551663,"threshold_uncertainty_score":0.00519079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01022567488002352,"score_gpt":0.2650628556190909,"score_spread":0.2548371807390674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}