{"id":"W2541175640","doi":"10.1002/pros.23269","title":"Suppression of LIM and SH3 Domain Protein 1 (LASP1) Negatively Regulated by Androgen Receptor Delays Castration Resistant Prostate Cancer Progression","year":2016,"lang":"en","type":"article","venue":"The Prostate","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Terry Fox Research Institute; Prostate Cancer Canada","keywords":"LNCaP; Prostate cancer; Cell growth; Cell cycle; Cancer research; Androgen receptor; Gene knockdown; Biology; Endocrinology; Cyclin D1; Internal medicine; Cancer; Medicine; Cell culture; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004937395,0.0002067041,0.0003472959,0.00004871691,0.0002064505,0.00001911664,0.00006433616,0.00007356874,0.0000307277],"category_scores_gemma":[0.00007133652,0.00009966331,0.00005995061,0.0001765914,0.0003712089,0.000139334,0.0001004048,0.0001126171,0.000003510589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006758743,"about_ca_system_score_gemma":0.00009453578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006710789,"about_ca_topic_score_gemma":0.00001863239,"domain_scores_codex":[0.9985387,0.000163967,0.0003642193,0.0003225814,0.0003174322,0.0002931479],"domain_scores_gemma":[0.9991122,0.0000577366,0.0002611041,0.0002615727,0.0002115032,0.00009585619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004817863,0.00006445385,0.001947227,0.0001687035,0.00009089205,0.000009899652,0.003641353,3.711172e-7,0.9474431,0.00005344145,0.003257317,0.03850537],"study_design_scores_gemma":[0.004007896,0.001114055,0.009939004,0.002604824,0.0001408345,0.00003255299,0.0008264293,0.0000130059,0.9671067,0.0008211883,0.01316373,0.0002297671],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988481,0.002909237,0.0000259394,0.005591588,0.00007499561,0.002355283,0.0003307313,0.00005556628,0.0001756342],"genre_scores_gemma":[0.9954873,0.001102154,0.0005001505,0.00003444881,0.00005256507,0.000390085,0.00002858315,0.00003048565,0.002374284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0382756,"threshold_uncertainty_score":0.4064152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01022567488002352,"score_gpt":0.2650628556190909,"score_spread":0.2548371807390674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}