{"id":"W2541240267","doi":"10.1007/s00125-016-4125-y","title":"Immunogenicity of human embryonic stem cell-derived beta cells","year":2016,"lang":"en","type":"article","venue":"Diabetologia","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juvenile Diabetes Research Foundation","funders":"Leids Universitair Medisch Centrum; European Commission; Seventh Framework Programme; Juvenile Diabetes Research Foundation International","keywords":"Biology; Cytotoxic T cell; Progenitor cell; Embryonic stem cell; Immune system; Stem cell; Immunology; Transplantation; Pancreatic islets; Cell biology; Acquired immune system; Cancer research; Islet; Insulin; Internal medicine; In vitro; Medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001778519,0.0001636423,0.0005165149,0.00008802847,0.00005668909,0.00000542891,0.0001273021,0.0001405072,0.0006534144],"category_scores_gemma":[0.0000296052,0.0001019889,0.0001647077,0.0001330387,0.0001806078,0.00005154256,0.00005496043,0.00009180359,0.0002687668],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005144807,"about_ca_system_score_gemma":0.00006146398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001222315,"about_ca_topic_score_gemma":6.073649e-7,"domain_scores_codex":[0.9988727,0.0000663316,0.0003171334,0.0002530892,0.0001787936,0.0003119337],"domain_scores_gemma":[0.9989535,0.0001881823,0.0001617775,0.0004723836,0.0001075995,0.0001165122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004381793,0.0001349843,0.05601303,0.00007498345,0.0000753224,0.000004596839,0.00004512309,2.03664e-7,0.9399856,0.0002216798,0.001594695,0.00180592],"study_design_scores_gemma":[0.001995713,0.0003880961,0.08080611,0.00008380249,0.0001122836,0.000001653803,0.00007264253,0.000005976874,0.9158622,0.00004695898,0.0005041024,0.0001204401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906598,0.0005400975,0.00007462881,0.000224594,0.0002172147,0.0002173696,0.00002095695,0.0001006381,0.007944652],"genre_scores_gemma":[0.9949936,0.00004645927,0.0001241557,0.0001917967,0.00004319238,0.00001603708,0.000009447596,0.00001741135,0.004557948],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02479308,"threshold_uncertainty_score":0.715443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01926516850537992,"score_gpt":0.2453216665383687,"score_spread":0.2260564980329887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}