{"id":"W2542372422","doi":"10.3390/insects7040060","title":"Sodium Channel Mutations and Pyrethroid Resistance in Aedes aegypti","year":2016,"lang":"en","type":"review","venue":"Insects","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":182,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Knockdown resistance; Pyrethroid; Biology; Aedes aegypti; Sodium channel; Gene knockdown; Genetics; Aedes; Dengue fever; Gene; Virology; Toxicology; Biotechnology; Sodium; Pesticide; Botany; Ecology; Larva","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001267908,0.000293605,0.001119771,0.0002070903,0.00005245221,0.00002871954,0.0001004359,0.0002146354,0.00008536602],"category_scores_gemma":[0.000150857,0.0002049427,0.0002251442,0.0002013541,0.00008778555,0.00005331355,0.00003898633,0.0002232643,0.00007327627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000933707,"about_ca_system_score_gemma":0.000378042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002788775,"about_ca_topic_score_gemma":0.000155256,"domain_scores_codex":[0.9986067,0.00007836386,0.0004096981,0.0004264665,0.0001798813,0.0002989016],"domain_scores_gemma":[0.9990472,0.0001805717,0.0001648893,0.0003731111,0.00005736379,0.0001769284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000807849,0.0001097101,0.00001895155,0.01883041,0.0001391369,0.0003535061,0.0001633026,1.953981e-8,0.000003779047,0.0008723093,0.001423414,0.9780047],"study_design_scores_gemma":[0.001223364,0.00007156037,0.0005082646,0.02918413,0.0005518195,0.00003294683,0.00001861736,0.000002526348,0.000001137064,0.0008280564,0.9673001,0.0002774954],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001061401,0.9935408,0.00001278586,0.0002994716,0.0001729413,0.0009066466,0.00008979384,0.0000431458,0.004828307],"genre_scores_gemma":[0.003937863,0.9928759,0.00003250497,0.0001982228,0.0003649933,0.0002952721,0.00006405445,0.00005070953,0.002180469],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9777272,"threshold_uncertainty_score":0.835732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03510695189868106,"score_gpt":0.332680436345151,"score_spread":0.29757348444647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}