{"id":"W2543204292","doi":"10.1016/j.juro.2016.10.069","title":"The Effect of Metformin Use during Docetaxel Chemotherapy on Prostate Cancer Specific and Overall Survival of Diabetic Patients with Castration Resistant Prostate Cancer","year":2016,"lang":"en","type":"article","venue":"The Journal of Urology","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Docetaxel; Prostate cancer; Metformin; Oncology; Internal medicine; Chemotherapy; Castration; Cancer; Prostate; Urology; Insulin; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006475976,0.0001550106,0.0002195881,0.0003593716,0.0003369717,0.0004840585,0.0002673016,0.000229614,0.0007670881],"category_scores_gemma":[0.00234032,0.0001225881,0.0006197551,0.0007174945,0.0001586119,0.0002369098,0.0002240322,0.0004031188,0.00006747568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009829862,"about_ca_system_score_gemma":0.0008354564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01771123,"about_ca_topic_score_gemma":0.03891473,"domain_scores_codex":[0.9995674,0.00009784014,0.00004403193,0.00008804802,0.0001111737,0.00009141464],"domain_scores_gemma":[0.9982479,0.0002663733,0.001021186,0.00008232689,0.0001209406,0.0002614687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005126325,0.00002887564,0.9978535,0.000008523739,0.00006827201,0.00002817674,0.00002090511,0.00003072372,0.00006874758,0.000005662725,0.00004147352,0.001332489],"study_design_scores_gemma":[0.00001039608,0.0001577216,0.9994561,0.00000395636,0.0000552241,0.00006390701,0.0000332819,0.00008009926,0.0000313512,0.000004556132,0.000101541,0.000001950403],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988329,0.0005039597,0.00002028609,0.00003263602,0.000005073869,0.000004672248,0.0003417927,0.000001239032,0.0002574114],"genre_scores_gemma":[0.9995189,0.0001041233,0.00002317084,0.00001460684,0.000005025692,0.000002670777,0.0002587165,4.466208e-7,0.0000722722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01771123,"threshold_uncertainty_score":0.03521627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005184841986433296,"score_gpt":0.2192506645443763,"score_spread":0.214065822557943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}