{"id":"W2543470710","doi":"10.1002/jcb.25774","title":"Phosphofructokinase‐P Modulates P44/42 MAPK Levels in HeLa Cells","year":2017,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Phosphofructokinase; HeLa; Downregulation and upregulation; MAPK/ERK pathway; Gene silencing; Cancer cell; Cell biology; Glycolysis; Cancer research; Chemistry; Cell; Biology; Cancer; Kinase; Biochemistry; Enzyme; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004827593,0.0002823955,0.0004268439,0.00006913977,0.0001477781,0.0001182668,0.0008283799,0.0003519213,0.00007556102],"category_scores_gemma":[0.0001592865,0.0002721341,0.0003295641,0.00005718827,0.0001777335,0.00001763034,0.0002029268,0.0003354786,0.000008548011],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004217252,"about_ca_system_score_gemma":0.0002741847,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002819451,"about_ca_topic_score_gemma":0.00000765744,"domain_scores_codex":[0.9983249,0.00003451623,0.0005864821,0.0003477528,0.000315192,0.0003911985],"domain_scores_gemma":[0.9979321,0.00001023115,0.0007557019,0.0008666428,0.0002159103,0.000219435],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001194659,0.0001053111,0.00056902,0.00006016549,0.0000715664,0.0000456067,0.00003067774,0.00005144603,0.9939682,0.000006003779,0.003038198,0.001934297],"study_design_scores_gemma":[0.001469122,0.00008525735,0.001928203,0.00008539642,0.000043478,0.0001043934,0.00006204272,0.00001896743,0.9637108,0.00009645961,0.03209504,0.0003007996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984323,0.01219673,0.0004139528,0.0001292828,0.001674268,0.00008683784,0.00003639048,0.000004287821,0.001135249],"genre_scores_gemma":[0.9925019,0.001026814,0.0007840727,0.00009878962,0.002851091,0.000003275981,0.00001889015,0.00003936367,0.002675814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0302574,"threshold_uncertainty_score":0.9999731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01041662081284244,"score_gpt":0.2447982764506346,"score_spread":0.2343816556377921,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}