{"id":"W2543679265","doi":"10.1182/blood-2016-06-723742","title":"Sensing of the microbiota by NOD1 in mesenchymal stromal cells regulates murine hematopoiesis","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":129,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Uehara Memorial Foundation; McGill University","keywords":"Haematopoiesis; NOD1; Mesenchymal stem cell; Cell biology; Biology; Stromal cell; Immunology; Bone marrow; Cancer research; Stem cell; Innate immune system; Immune system; NOD2","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000211371,0.0003064063,0.0002727729,0.0003501003,0.0001551262,0.0003353217,0.0001717277,0.0002417691,0.0007780211],"category_scores_gemma":[0.00009664857,0.0001754683,0.0002101604,0.0001553496,0.000264223,0.000150955,0.0002217654,0.0007306841,0.0003453334],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003004204,"about_ca_system_score_gemma":0.0002139424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002805039,"about_ca_topic_score_gemma":0.0006275073,"domain_scores_codex":[0.9997737,0.00006121368,0.00002664627,0.00002955237,0.00004957022,0.0000592796],"domain_scores_gemma":[0.9998318,0.00002459989,0.00004333304,0.00001786421,0.00001175389,0.0000705781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001437715,0.00004547818,0.0001539853,0.00001739191,0.000001894295,0.00004257101,0.000016714,0.0001077012,0.9982713,0.0001374251,0.00002058075,0.00104115],"study_design_scores_gemma":[0.00004126245,0.0004808285,0.002597797,0.00001019057,0.0000128701,0.0001297826,0.00004410957,0.00173891,0.9935356,0.00007985497,0.001325098,0.000003717734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995757,0.000957584,0.001826061,0.00007553749,0.00001926482,0.00002284641,0.0002588478,0.00006843763,0.001014473],"genre_scores_gemma":[0.9960738,0.0004351397,0.001760764,0.00004113089,0.000008921575,0.00002961697,0.0002158671,0.00001896911,0.001415709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007780211,"threshold_uncertainty_score":0.002602756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006124906220608337,"score_gpt":0.2064137756012773,"score_spread":0.2002888693806689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}