{"id":"W2545396337","doi":"10.1182/blood.v104.11.3440.3440","title":"Ship Is Essential for Both Endotoxin- and CpG-Induced Tolerance and for Their Cross-Tolerance.","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; BC Cancer Agency","funders":"","keywords":"Lipopolysaccharide; Autocrine signalling; TLR4; Biology; Cell biology; TLR9; Cytokine; Downregulation and upregulation; Receptor; Immune tolerance; Immunology; Haematopoiesis; Signal transduction; Immune system; Gene expression; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008705744,0.0001450841,0.0002479009,0.00004546631,0.0001773925,0.0000636027,0.00004141638,0.00007475782,0.00002638053],"category_scores_gemma":[0.00005743955,0.0001219579,0.0001009664,0.00005007909,0.00005201236,0.00009340859,0.00001566168,0.00009899298,0.000001583585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001158759,"about_ca_system_score_gemma":0.00006471054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003324142,"about_ca_topic_score_gemma":0.00001573491,"domain_scores_codex":[0.9992037,0.000004943613,0.0001977706,0.0002903544,0.00007721476,0.000225974],"domain_scores_gemma":[0.9995022,0.00008376726,0.00006205673,0.0001610783,0.00008877058,0.0001021226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000410928,0.00046219,0.002462222,0.0002581149,0.0001188251,0.000006352068,0.0009698628,0.000007173694,0.9919802,0.001319329,0.0002657776,0.001739024],"study_design_scores_gemma":[0.01281113,0.0007410498,0.005512386,0.0002022246,0.0001469532,0.0001424883,0.00007430528,0.0001627296,0.9716694,0.001547946,0.006821635,0.0001677115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953687,0.0004819191,0.001883947,0.000727571,0.0002091642,0.000767925,0.0001527187,0.00004502105,0.0003631018],"genre_scores_gemma":[0.9965355,0.00003546981,0.001674471,0.0006714426,0.0006407561,0.0002192853,0.00001763609,0.00002802307,0.0001773868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02031076,"threshold_uncertainty_score":0.4973298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03327556308504895,"score_gpt":0.314531125780951,"score_spread":0.2812555626959021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}