{"id":"W2545396337","doi":"10.1182/blood.v104.11.3440.3440","title":"Ship Is Essential for Both Endotoxin- and CpG-Induced Tolerance and for Their Cross-Tolerance.","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; BC Cancer Agency","funders":"","keywords":"Lipopolysaccharide; Autocrine signalling; TLR4; Biology; Cell biology; TLR9; Cytokine; Downregulation and upregulation; Receptor; Immune tolerance; Immunology; Haematopoiesis; Signal transduction; Immune system; Gene expression; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001740363,0.0003222423,0.0001589968,0.0001318021,0.00009739492,0.0002165055,0.000180626,0.0002222243,0.002387891],"category_scores_gemma":[0.0001068306,0.0001414835,0.0003149228,0.00009501632,0.00023782,0.0002252881,0.0003354037,0.0005678423,0.000678581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001285191,"about_ca_system_score_gemma":0.0001054331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009939318,"about_ca_topic_score_gemma":0.0001338599,"domain_scores_codex":[0.9998796,0.00002229822,0.00001445353,0.0000235186,0.00003769809,0.00002242329],"domain_scores_gemma":[0.9998449,0.00001434992,0.00006532849,0.00002100685,0.00001527342,0.00003915351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007906663,0.000009748887,0.0001877525,0.00003771908,0.000002688823,0.00005698047,0.00000459381,0.00001364096,0.9987948,0.00009393533,0.00001767974,0.0007013733],"study_design_scores_gemma":[0.00002862304,0.0004553451,0.02279384,0.00001075562,0.00002779613,0.001002028,0.00003698875,0.0006269134,0.9699475,0.0001438608,0.004921279,0.000005106554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920643,0.002990876,0.003377207,0.0001346626,0.00005616651,0.00001920396,0.0002389066,0.00004026208,0.001078412],"genre_scores_gemma":[0.991714,0.001417605,0.002076365,0.00008563852,0.00002197499,0.00003095407,0.0007452522,0.00001714458,0.003891183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002387891,"threshold_uncertainty_score":0.007988274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03327556308504895,"score_gpt":0.314531125780951,"score_spread":0.2812555626959021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}