{"id":"W2545577014","doi":"10.3390/v8110297","title":"The Importance of Physiologically Relevant Cell Lines for Studying Virus–Host Interactions","year":2016,"lang":"en","type":"review","venue":"Viruses","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Immortalised cell line; Cell culture; Biology; Interferon; Virus; Cell biology; Phenotype; Primary cell; Viral replication; Cell; Innate immune system; Virology; Gene; Immunology; Genetics; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003200257,0.0003782639,0.00118035,0.000105231,0.0003476999,0.00002128334,0.0006136837,0.0002932235,0.0002761868],"category_scores_gemma":[0.0005101691,0.0001765109,0.0006410371,0.00009618779,0.0003260369,0.00007201314,0.0001942129,0.0003435356,0.0005582191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004599886,"about_ca_system_score_gemma":0.0001687182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000113145,"about_ca_topic_score_gemma":0.00002144772,"domain_scores_codex":[0.9978947,0.0004267262,0.0009247585,0.0003523176,0.00003023127,0.0003712342],"domain_scores_gemma":[0.994678,0.003791828,0.0008253366,0.0005532212,0.0001381305,0.00001345163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009548736,0.0004185789,0.00001007956,0.003285346,0.001340169,0.000002559566,0.00009860881,5.689279e-8,0.2839352,0.001127181,0.02325515,0.6855722],"study_design_scores_gemma":[0.0002552785,0.0003152686,0.000009079671,0.003342435,0.0002273825,0.00001426225,0.00005884386,3.842416e-8,0.01807885,0.00003101211,0.9774458,0.0002217274],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005097214,0.9962575,0.00003788366,0.00003175757,0.00148808,0.0008399198,0.0005012303,0.00004994125,0.000283933],"genre_scores_gemma":[0.0002700643,0.9930215,0.00002821897,0.000109818,0.0000987719,0.0003182515,0.00004630853,0.00004373813,0.006063257],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9541907,"threshold_uncertainty_score":0.7197908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08750252382150983,"score_gpt":0.3665548050235424,"score_spread":0.2790522812020326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}