{"id":"W2545577014","doi":"10.3390/v8110297","title":"The Importance of Physiologically Relevant Cell Lines for Studying Virus–Host Interactions","year":2016,"lang":"en","type":"review","venue":"Viruses","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Immortalised cell line; Cell culture; Biology; Interferon; Virus; Cell biology; Phenotype; Primary cell; Viral replication; Cell; Innate immune system; Virology; Gene; Immunology; Genetics; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001445984,0.0008659385,0.001643751,0.001740234,0.0004029958,0.001526879,0.001094304,0.001522676,0.002221154],"category_scores_gemma":[0.0008552537,0.0003098285,0.0005606581,0.001399272,0.0011483,0.002291026,0.000834149,0.003403958,0.002205605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007921352,"about_ca_system_score_gemma":0.0009233631,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005653856,"about_ca_topic_score_gemma":0.0008193257,"domain_scores_codex":[0.9995727,0.00009071775,0.00006641059,0.000068068,0.0001665305,0.00003550712],"domain_scores_gemma":[0.9993089,0.0003649142,0.00007720837,0.00005234453,0.0001359526,0.00006069009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001032942,0.0001110525,0.0004239705,0.01727722,0.00006882859,0.0005748089,0.0002397632,0.0005300756,0.05572496,0.034043,0.02203188,0.8688711],"study_design_scores_gemma":[0.000006372034,0.00006377582,0.0004217532,0.000999859,0.00003542374,0.0009686063,0.00006803885,0.00005432882,0.00596317,0.003239866,0.98816,0.00001875444],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003257117,0.9950324,0.001132316,0.0004405095,0.000549092,0.00001403166,0.00004329065,0.00001797551,0.002444685],"genre_scores_gemma":[0.001911161,0.9939889,0.002053943,0.0002985228,0.0002572024,0.00003621441,0.0001092583,0.000009953797,0.001334835],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002221154,"threshold_uncertainty_score":0.007647157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08750252382150983,"score_gpt":0.3665548050235424,"score_spread":0.2790522812020326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}