{"id":"W2546689982","doi":"10.1182/blood.v126.23.4416.4416","title":"A Point-of-Care Platform for Hematopoietic Stem Cell Gene Therapy","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Progenitor cell; Genetic enhancement; CD34; Haematopoiesis; Bone marrow; Stem cell; Plerixafor; Medicine; Cell therapy; Immunology; Hematopoietic stem cell; Ex vivo; Cancer research; Biology; CXCR4; Cell biology; In vivo; Gene; Biotechnology; Chemokine; Genetics; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004427044,0.0007855578,0.0004910621,0.0006628193,0.0002499843,0.0007800615,0.0008157328,0.0006450837,0.006555371],"category_scores_gemma":[0.0003289902,0.0003374813,0.0005370181,0.0002369791,0.0002338489,0.0004387943,0.0007996312,0.0009365014,0.006244111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002670369,"about_ca_system_score_gemma":0.0003874289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001871719,"about_ca_topic_score_gemma":0.0002452439,"domain_scores_codex":[0.9994486,0.00008517534,0.00002716734,0.0001100333,0.0002694014,0.00005964861],"domain_scores_gemma":[0.9997824,0.00003323816,0.00004912943,0.00004063437,0.00004651379,0.00004815952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009591691,0.0000973632,0.0001708401,0.00005821723,0.000007765984,0.00009449779,0.00001807617,0.0002859402,0.9843099,0.0004612007,0.001129709,0.01327055],"study_design_scores_gemma":[0.00005344756,0.001168127,0.001684675,0.00002642888,0.0000406368,0.0008398957,0.00002064257,0.004686161,0.9557939,0.0003874022,0.03526521,0.00003350381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1779944,0.001302522,0.7963588,0.0002691514,0.000354161,0.002415987,0.002953625,0.01034749,0.008003918],"genre_scores_gemma":[0.3495624,0.00161082,0.617065,0.0003642756,0.0001227636,0.00312133,0.006790148,0.0009213401,0.02044198],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.006555371,"threshold_uncertainty_score":0.02192992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0337217936459812,"score_gpt":0.2908226015919771,"score_spread":0.2571008079459959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}